摘要
目的总结中国早发型多发性硬化(EOMS)的临床特点。方法从临床、辅助检查等方面对32例EOMS病例进行回顾性分析。结果EOMS好发于10岁后儿童,无性别差异,急性起病为主,首发症状以肢体无力多见,视力、运动和感觉障碍是EOMS患者最常见的症状,可合并周围神经系统损害,诱发电位检查阳性率较高,影像学改变以大脑半球和脊髓受累多见。结论EOMS是多发性硬化的一个亚型,其起病急、症状多样但预后较好,诱发电位和影像学检查对EOMS诊断有一定意义。
Objective To summarize the features of early onset multiple sclerosis （EOMS） in China. Methods The clinical manifestations and inducements of 32 EOMS patients were comprehensively analyzed using clinical statistical method. Results Onset occurred after 10 years in 24 of the 32 children, gender difference was not observed. EOMS was found mostly acute in onset and usually due to an inducement. The first seen symptom mainly showed limb weakness. Visual disturbance presentation was the predominate feature. The peripheral nervous system damage showed by electromyography might occur in EOMS. Cerebral hemisphere and spinal cord were mostly found to be invaded according to MRI. Conclusions EOMS was a subtype of the multiple sclerosis （MS）. MR/and evoked potentials could help its diagnosis.
出处
《中国神经免疫学和神经病学杂志》
CAS
2008年第1期23-26,共4页
Chinese Journal of Neuroimmunology and Neurology
关键词
儿童
多发性硬化
诊断
childhood
multiple sclerosis
diagnosis
