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防风通圣丸联合氯雷他定治疗慢性荨麻疹疗效观察 被引量:6

The observation about the curative effective of Fangfengtongsheng pill combining loratadine in the therapy of chronic urticaria
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摘要 目的观察防风通圣丸联合氯雷他定治疗慢性荨麻疹的疗效及安全性。方法将79例慢性荨麻疹患者随机分为2组。治疗组43例,口服氯雷他定10mg,每日一次,防风通圣丸6g,每日2次,连服3周;对照组36例,口服氯雷他定10mg,每日1次,连服3周。治疗结束后3个月观察两组的疗效及不良反应。结果治疗组总有效率为90.7%,对照组有效率72.22%,两组比较差异有统计学意义(P<0.05),未见明显不良反应。结论防风通圣丸联合氯雷他定治疗慢性荨麻疹疗效好且安全性高,可供临床应用。 Objective To observe the curative effect and safety of Fangfengtongsheng pill combining loratadine in the therapy of chronic urticaria. Methods 79 chronic urticaria patients were randomly divined into 2 groups. The therapy group has 43 patients, the control group has 36 patients. The patients in the therapy group took loratadine 10mg Qd and Fangfengtongsheng pill 6g Bid; the patients in the control group took loratadine 10mg Qd. The course is 3 weeks. In 3 months after the therapy course ending, the curative effect and safety were observed. Results the effective rate of the therapy group is 90.7%, the control group is 72.22%, no obviously adverse effect was observed. Conclusions Fangfengtongsheng pill combining loratadine has better curative curative effect and safety.
出处 《海南医学》 CAS 2008年第1期54-54,29,共2页 Hainan Medical Journal
关键词 慢性荨麻疹 防风通圣丸 氯雷他定 chronic urticaria Fangfengtongsheng pill loratadine
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  • 1[1]Kay GG, Harris AG. Loratadine: a non-sedating antihistamine. Review of its effects on cognition, psychomotor performance, mood and sedation[J]. Clin Exp Allergy, 1999, 29(Suppl 3): 147-150.
  • 2[2]Simons FE, McMillan JL, Simons KJ. A double-blind, singledose, crossover comparison of cetirizine, terfenadine, loratadine,astemizole, and chlorpheniramine versus placebo: Suppressive effects on histamine-induced wheals and flares during 24 hours in normal subjects[J]. J Allergy Clin Immunol, 1990, 86(4 Pt 1):540-547.

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