摘要
自赤芝［Ｇａｎｏｄｅｒｍａｌｕｃｉｄｕｍ（Ｆｒ．）Ｋａｒｓｔ．］子实体的二氯甲烷提取物中分离得到一个新的四环三萜化合物，命名为灵芝酸ＤＭ（ｇａｎｏｄｅｒｉｃａｃｉｄＤＭ，Ｉ）。根据光谱（ＵＶ，ＩＲ，１ＨＮＭＲ，１３ＣＮＭＲ，ＭＳ２ＤＮＭＲ）分析，确定其结构为Ｉ式。同时还分离得到二个已知的灵芝酸类化合物，即灵芝酸Ａ（ｇａｎｏｄｅｒｉｃａｃｉｄＡ，Ｉ）和灵芝酸Ｃ（ｇａｎｏｄｅｒｉｃａｃｉｄＣ，ＩＩ）。
Three compounds have been isolated from the dichloromethane soluble fraction of the fruiting body of Ganoderma lucidum (Fr.) Karst. On basis of spectral analyses (UV, IR, MS, 1HNMR, 13 CNMR and 2D NMR), they were identified as 3,7 dioxo lanosta 8,24( E ) dien 26 oic acid (I), 7β 15α dihydroxy 3,11,23 trioxo 5α lanost 8 en 26 oic acid (II) and 3β,7β,15α trihydroxy 11,23 dioxo 5α lanosta 8 en 26 oic acid (III). Compound I is a new compound named ganoderic acid DM.
出处
《药学学报》
CAS
CSCD
北大核心
1997年第6期447-450,共4页
Acta Pharmaceutica Sinica
