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重组人干扰素α-1b治疗婴幼儿轮状病毒肠炎疗效观察 被引量:1

Effect of interferon α-1b injection therapy rotavirus enteritis
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摘要 目的:观察干扰素(IFN)治疗轮状病毒肠炎的临床疗效。方法:选择2006年9月至2007年3月门诊的轮状病毒肠炎患儿82例,随机分成治疗组45例和对照组37例,两组在常规治疗基础上分别给予干扰素和利巴韦林治疗。结果:经72 h治疗后,干扰素治疗组有效率91.11%,对照组51.35%,两者比较差异有统计学意义。结论:干扰素治疗轮状病毒肠炎可显著提高有效率,缩短病程。 Objective: To observe the effect of interferon α-1b injection in treatment of rotavirus enteritis. Methods: Patients with rotavirus enteritis from September 2006 to March 2007 were divided into treatment group and control group. The two groups were given interferon α-1b injection and ribavin regulations respectively in addition to the conventional treatment. Results: At the end of 72 hours' treatment, the efficiency rate of the group of interferon α-1b injection treatment was 91.11% and that of the control one was 51.35 %. There was a statistical significance between two groups. Conclusions: Application of interferon α-1b injection in treating rotavirus enteritis can increase efficacy and reduce the course of disease.
作者 李春舒 赵昕
出处 《儿科药学杂志》 CAS 2007年第6期52-53,共2页 Journal of Pediatric Pharmacy
关键词 重组人干扰素Α-1B 婴幼儿 轮状病毒 肠炎 Recombinant Human interferon α-lb injection Infants Rotavirus enteritis
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