摘要
目的观察干扰素(IFN)在治疗轮状病毒(HRV)肠炎中的临床疗效及免疫功能的变化。方法70例HRV肠炎患儿随机分为常规治疗的对照组和常规治疗加用小剂量IFN的治疗组,观察两组患儿治疗的临床疗效及免疫功能变化。结果治疗组总有效率85.8%,明显高于对照组57.1%(P<0.01),且治疗组免疫功能较治疗前明显提高。结论小剂量IFN有助于提高临床疗效,恢复患儿免疫功能。
Objectives To investigate the clinical effects of interferon in the treatments of the infants with rotaviral enteritis and to observe the immunological changes of the patients. Methods 70 infants with rotaviral enteritis were divided into the treated group and the control group randomly. The patients in the control group were treated with regular method without interferon while those in the treated group were received low-dose interferon additionally. The clinical effects of interferon and the immunological changes were investigated. Results The total effective rate of the treated group was higher than that of the control group （85.8% vs 57. 1% , P 〈 0. 01 ） , and the immunological indicators of the patients in the treated group were improved as well. Conclusion Low-dose interferon can enhance the therapeutic effects and improve the immunity of the rotaviral enteritis infants.
出处
《实用医院临床杂志》
2009年第4期89-90,共2页
Practical Journal of Clinical Medicine
