摘要
对汕头市２３６例临床诊断中枢神经系统（ＣＮＳ）感染患者进行肠道病毒（ＥＶ）病原学及血清学检测，结果从２３６例的２５７份标本中分离出病毒６２株（５５例），检出率为２４．１％。５７例患者做了双份血清检测，中和抗体≥４倍增高者４８例，阳性率为８４．２％。以上患者病毒分离和／或血清学阳性而确诊者７８例，确诊率为３３．１％，患者感染的病毒型别分布及构成比分别为：脊髓灰质炎（Ｐｏｌｉｏ）病毒３３例（０．４２３１），其中Ⅰ型６例、Ⅱ型１８例、Ⅲ型４例和多型混合感染５例；柯萨奇（Ｃｏｘ）病毒２１例（０．２６９２），其中Ａ２４型６例、Ｂ１型７例、Ｂ４型２例和Ｂ５型６例；埃可（ＥＣＨＯ）病毒１１例（０．１４１０），其中７型５例、２４型２例和１１、１２、１５、２７型各１例；肠道病毒１０例（０．１２８０），其中７０型３例、７１型７例及多种病毒混合感染３例（０．０３８５）。
Enterovirus isolation and serological assay were done in 236 cases of CNS infection in Shantou. 62 strains of virus (from 55 cases) were isolated from 257 samples of 236 cases (24.1%). 48 cases were positive among 57 cases (84.2%) by serological assay. 78 cases were positive for virus isolation and/or serological assay (33.1%). Virus infection included 33 cases of poliovirus (including 6 polio-Ⅰ、18 polio-Ⅱ、4 polio-Ⅲ、5 mixed infections), 21 cases of Coxsackie virus (including 6 CoxA24、7 CoxB1、2 CoxB4 and 6 CoxB5), 11 cases of ECHO virus (including 5 ECHO-7、2 ECHO-24 and each one of ECHO-11、12、15、27), 10 cases of Enterovirus (including 3 EV-70、7 EV-71), and 3 cases of mixed viral infection.
出处
《中华实验和临床病毒学杂志》
CAS
CSCD
1997年第2期174-176,共3页
Chinese Journal of Experimental and Clinical Virology
关键词
肠道病毒
脑
中枢神经系统
疾病
Enterovirus Brian/Virology Central nervous system Antibody, viral
