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糖基化终产物在牙周病中的作用 被引量:3

The role of advanced glycation end products in periodontal diseases
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摘要 糖基化终产物(AGEs)是非酶性糖基化反应产生的一组异源性物质。AGEs在糖尿病患者的组织、血浆中蓄积是造成糖尿病慢性并发症原因之一。近年来亦发现AGEs与其受体作用的加强是糖尿病患者牙周病加重的发病机制之一。本文主要就AGEs及其受体在牙周病中的作用和相关机制作一概述。 The advanced glycation end products (AGEs) is a heterogeneous group of compounds of nonenezymatic glycosation reactions. The accumulation of AGEs in diabetic patients' tissue and blood may contribute to the developmemt of diabetic complications. Recently, it has also been found that the enhanced interaction between AGEs and its'receptor was one of the pathogenesises of aggravated periodontal diseases. The objective of this review is to clarify the role of AGEs and its'receptor in periodontal diseases and the correlative mechanism.
作者 齐刘英 付云
出处 《国际口腔医学杂志》 CAS 2007年第6期433-436,共4页 International Journal of Stomatology
关键词 糖基化终产物 糖基化终产物受体 牙周病 糖尿病 advanced glycation end products receptor for advanced glycation end products periodontal diseases diabetes mellitus
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参考文献21

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同被引文献11

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  • 9王万春,吴宁,尚振平,陈青.糖基化终产物对牙周膜成纤维细胞增殖的影响[J].临床口腔医学杂志,2008,24(9):526-528. 被引量:3
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