摘要
糖基化终产物(AGEs)是非酶性糖基化反应产生的一组异源性物质。AGEs在糖尿病患者的组织、血浆中蓄积是造成糖尿病慢性并发症原因之一。近年来亦发现AGEs与其受体作用的加强是糖尿病患者牙周病加重的发病机制之一。本文主要就AGEs及其受体在牙周病中的作用和相关机制作一概述。
The advanced glycation end products (AGEs) is a heterogeneous group of compounds of nonenezymatic glycosation reactions. The accumulation of AGEs in diabetic patients' tissue and blood may contribute to the developmemt of diabetic complications. Recently, it has also been found that the enhanced interaction between AGEs and its'receptor was one of the pathogenesises of aggravated periodontal diseases. The objective of this review is to clarify the role of AGEs and its'receptor in periodontal diseases and the correlative mechanism.
出处
《国际口腔医学杂志》
CAS
2007年第6期433-436,共4页
International Journal of Stomatology
关键词
糖基化终产物
糖基化终产物受体
牙周病
糖尿病
advanced glycation end products
receptor for advanced glycation end products
periodontal diseases
diabetes mellitus