摘要
罗红霉素对一些特殊致病原如军团菌，肺炎支原体，肺炎衣原体等引起的呼吸道感染，泌尿道感染，皮肤软组织感染等有较好的疗效。它的抗菌特点，机制，药代动力学特点相对较好，组织细胞内的药物浓度和血药浓度较高，体内分布广，药物不良反应小。
Roxithromycin is effective in the treatment of respiratory tract infections, urinary tract infections, skin & skin tissue infections caused by the specific pathogens such as Legionella pneumophitsia, Mycoplasma pneumoniae, Chlamydia. This drug has good antibacterial activity, pharmacokinetic characteristics which make it acheive a high drug concentration both in blood and in the intracellur level compared with other macrolide antibiotics. It has a long half-life, wide distribution in the body fluids. Clinical results indicated this drug was well tolerated and adverse reaction was relatively minimal.
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
1997年第2期124-127,共4页
The Chinese Journal of Clinical Pharmacology
关键词
罗红霉素
抗菌活性
药代动力学
呼吸道感染
roxithromycin
antimicrobial activity
pharmacokinetics
clinical use
