摘要
目的研究急性脑梗死患者治疗前后血小板相关参数的变化。方法以本院住院的67例急性脑梗死患者为研究对象,利用流式细胞仪、CoulterSTKS血球仪同时进行血小板计数(PLT)、血小板平均体积(MPV)、血小板分布宽度(PDW)、血小板膜糖蛋白(CD62P、CD63)、血小板比容(PCT)检测,观察治疗前后血小板相关参数的变化。结果脑梗死患者治疗前的PLT、MPV、PDW、CD62P、CD63、PCT分别是(155.73±54.73)×109/L,(9.56±0.27)fl,(16.24±0.35)%,(6.24±3.79)%,(6.23±3.54)%,(0.15±0.07)%;治疗后分别是(175.45±62.49)×109/L,(9.16±0.64)fl,(17.03±0.67)%,(0.98±0.57)%,(2.25±1.50)%,(0.16±0.02)%。MPV、PDW、CD62P、CD63、PCT治疗前后差异有统计学意义(P<0.05)。结论血小板相关参数的检测结果治疗前后差异有统计学意义,提示与脑梗死的发病具有一定的相关性。
Objective To study the change of platelet relative parameters in the patients with acute cerebral infarction before and after treatment. Methods To detect platelet （PLT）, mean platelet volume （MPV）, platelet distribution width （PDW）, platelet membrane glycoproteins（ CD62P, CD63P）, platelet hematocrit （PCT） in 67 pa tients with acute cerebral infarction and to observe the change of relative parameters before and after treatment. Resuits The data before therapy displayed that PLT, MPV, PDW, CD62P, CD63P and PCT were （155.73±54.73）×10^9/L,（9.56±0.27）fl,（16.24±0.35）%,（6.24±3.79）%,（6.23±3.54）%,（0. 15±0.07）% respectively; and after therapy PLT, MPV, PDW, CD62P, CD63P and PCT were （175.45±62.49）×10^9/L,（9.16±0.64）fl,（17.03 ±0.67）%,（0.98±0.57）%,（2.25±1.50）%,（0.16±0.02）% respectively. MPV, PDW, CD62P, CD63 and PCT had significant difference before and after treatment （P〈0. 05）. Conclusion The detecting results of platelet rela rive parameters have significantly statistical difference before and after treatment, and these relative parameters have definite correlation with cerebral infarction attack.
出处
《检验医学与临床》
CAS
2007年第11期1036-1037,共2页
Laboratory Medicine and Clinic
关键词
脑梗死
血小板
血栓
cerebral infarction
platelet parameters
thrombus
