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膜乳化技术在微粒给药系统中的应用 被引量：3

Application of Membrane Emulsification Technology to Particulate Delivery Systems
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摘要 膜乳化技术可用于制备各种乳剂、微粒和脂质体等,制备过程能耗低,条件温和,设备简单,操作方便,有望实现扩大生产。本文综述了膜乳化过程、影响因素,及该技术在乳剂、微球、纳米粒等剂型制备中的应用。 Membrane emulsification technology can be used to prepare emulsions, particulates and liposomes. Because of the low energy expenditure, easy operation and simple equipment, membrane emulsification technology is hopeful for large scale production. Its procedure, influence effects and applications in preparing emulsions, microspheres and nanoparticles are reviewed.
作者 顾立 李学明 陈国广
机构地区 南京工业大学制药与生命科学学院
出处 《中国医药工业杂志》 CAS CSCD 北大核心 2007年第11期814-818,共5页 Chinese Journal of Pharmaceuticals
基金 江苏省自然科学基金(BK2006177)
关键词 膜乳化 单分散 微粒给药系统 综述 membrane emulsification monodisperse particulate delivery system review
分类号 R944.9 [医药卫生—药剂学]
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参考文献27

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共引文献28

同被引文献63

  • 1李保国,高建成,丁志华.高压静电成囊法工艺参数的优化[J].中国医药工业杂志,2004,35(8):472-474. 被引量：14
  • 2Richard A. Williams.Large scale manufacture of magnetic polymer particles using membranes and microfluidic devices[J].China Particuology,2007,5(1):26-42. 被引量：3
  • 3Park SB, Jeon YJ, Haam S, et al. Preparation of chitosan microspheres using membrane emulsification and its size modelling [J]. J Microencapsul, 2004, 21 (5) : 539-552.
  • 4Ito F, Fujimori H, Honnami H, et al. Effect of polyethylene glycol on preparation of rifampicin-loaded PLGA microspheres with membrane emulsification technique [J]. Colloids SurfBBiointerfaces, 2008, 66 (1) : 65-70.
  • 5Wei Q, Wei W, Tian R, et al. Preparation of uniform-sized PELA microspheres with high encapsulation efficiency of antigen by premix membrane emulsification [J]. J Colloid Interface Sci, 2008, 323 (2) : 267-273.
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  • 8San Romain B, Irache JM, Gomez S, et al. Co-encapsulation of an antigen and CpG oligonucleotides into PLGA microparticles by TROMS technology [J]. Eur J Pharm Biopharm, 2008, 70 (1): 98-108.
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引证文献3

二级引证文献6

中国医药工业杂志
2007年 第11期

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