摘要
目的:研究宁夏二年生栽培防风水煎液的镇痛、抗炎作用。方法:用扭体法、热板法观察栽培防风水煎液对小鼠的镇痛作用;用二甲苯致小鼠耳廓肿胀、小鼠棉球肉芽肿增生的方法观察栽培防风水煎液的抗炎作用;并与野生防风进行比较.结果:宁夏二年生栽培防风水煎液高、低剂量(60g/kg、30g/kg)能明显减少小鼠扭体次数(P<0.01),其高剂量(60g/kg)能抑制小鼠棉球肉芽肿增生(P<0.05);对热板法所致小鼠舔足时间和二甲苯所致小鼠耳廓肿胀具有一定的抑制作用.结论:宁夏二年生栽培防风水煎液具有一定的镇痛、抗炎作用,但其作用效果没有野生防风显著.
Objective： To study the analgesic and anti - inflammatory action of Saposhnicovia divaricata （SD） decoction which cultivated in Ningxia two years. Methods： Hot plates and writhing test were employed to observe the analgesic action of local cultivated SD decoction in mouse. Dimethyl benzene was used to worsen ear swelling and cotton - ball was used to cause granular proliferation for observing the anti - inflammatory effect of Ningxia local cultivated SD decoction comparing with the effect of wild SD decoction. Results： High and low dose of Ningxia local cultivated SD decoction （60g/kg,30g/kg） can reduce the writhing times of mouse （P〈0.01）, High dose group （60g/kg） can inhibit the granular proliferation caused by cotton- ball （P〈 0.05）and it has some effect of suppression on the licking- paw time in touche caused by hot plate and the ear swelling caused by Dimethhyl benzene. Conclusion： The SD decoction which cultivated in Ningxia two years has some effect of analgesia and anti - inflammation, but it is not as effective as wild SD decoction does.
出处
《黑龙江医药》
CAS
2007年第6期596-598,共3页
Heilongjiang Medicine journal
关键词
宁夏栽培防风
野生防风
镇痛
抗炎
Ningxia local cultivated SD
Wild SD
Analgesic
Anti - inflammatory
