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准分子激光上皮瓣下角膜磨镶术矫治高度近视

Laser-assisted subepithelial keratectomy for the correction of high myopia
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摘要 目的评价准分子激光上皮瓣下角膜磨镶术(LASEK)矫治高度近视的疗效。方法选取高度近视患者27例(54眼),术前近视等效球镜为-6.00^-14.00 D,平均(-8.75±1.27)D。观察术后角膜上皮修复时间、术后视力、角膜上皮下雾状混浊(Haze)、角膜地形图及屈光度数,随访时间为6个月。结果所有术眼术中及术后均无严重并发症发生。术后角膜上皮修复时间平均为(3.71±0.26)d。术后3 d,裸眼视力≥0.5者48眼(88.9%),≥0.8者19眼(35.2%),术后7 d,裸眼视力≥0.5者54眼(100.0%),≥0.8者47眼(87.0%),术后6个月,裸眼视力均达到或超过术前最佳矫正视力。术后1、3、6个月等效球镜均在-0.50^+0.50 D之间,术后1、3、6个月角膜Haze发生率分别为13眼(24.1%)、7眼(13.0%)、2眼(3.7%),但均小于2级,不影响视力恢复。结论LASEK治疗高度近视视力恢复好且稳定,无明显角膜上皮下雾状混浊及屈光回退。 Objective To investigate the effect of laser-assisted subepithelial keratectomy(LASEK) for the correction of high myopia. Methods LASEK was performed on 54 eyes of 27 myopia patients. The preoperative mean spherical (MSE) was - 6.00 ~ - 14.00 D, average( - 8.75 ± 1.27) D. Postoperative uncorrected visual acuity (UCVA), refractive power, time of epithelial healing and corneal haze were all recorded. Patients were followed-up for 6 months. Results No serious complications occurred. The epithelium was healed in a mean (3.71 ± 0.26) d. 3 days after the operations, the UCVA ≥ 0.5 was found in 88.9 % (48/54) and ≥ 0.8 in 35.2 % (19/54). 7 days after the operations, the UCVA≥0.5 was found in 100%(54/54) and ≥0.8 in 87.0% (47/54). 6 months after the operations the UCVA was equal with or better than the preoperative best corrected visual acuity (BCVA). 1, 3 and 6 months after the operations, corneal haze was found in 13 eyes(24.1%), 7 eyes(13.0%) and 2 eyes(3.7%)respectively but it was below grade 2 and had no effect on visual acuity. Conclusion LASEK is a safe, effective, stable and predictable surgery for myopia.
出处 《山东大学耳鼻喉眼学报》 CAS 2007年第5期465-467,共3页 Journal of Otolaryngology and Ophthalmology of Shandong University
关键词 准分子激光上皮瓣下角膜磨镶术 近视 视力 角膜上皮下雾状混浊 Laser-assisted subepithelial keratomileusis Myopia Visual acuity Corneal haze
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参考文献10

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二级参考文献8

  • 1Camellin M.LASEK may offer the advantages of both Lasik and PRK[J].J Ocu Surg N Int,1999,10(3):14-15.
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