期刊文献+

伊曲康唑联合达克宁栓治疗和预防复发性外阴阴道念珠菌病的疗效观察

暂未订购
导出
摘要 [目的]探讨伊曲康唑联合达克宁栓治疗和预防复发性外阴阴道念珠菌病的效果。[方法]A组给予伊曲康唑口服200 mg/d,连用3 d;同时将外阴洗净,每晚放一粒达克宁栓(400 mg/粒)入阴道后穹隆,连续用药3 d。B组与A组一样用药3 d,再连续6个月经周期用上述药物,每个周期3 d。[结果]两组冲击治疗1周时,两组痊愈率差异无显著性(x2= 0.02,P>0.5)。总有效率比较也无显著性(x2=0.002,P>0.5)。两组治疗后第3个月和第6个月时,两组的复发率比较有显著性差异(x2分别为6.12和8.73,P<0.001)。[结论]伊曲康唑短程冲击治疗联合达克宁栓加长期预防性给药对复发性外阴阴道念珠菌病的治疗和预防复发有一定疗效。
出处 《中山大学学报(医学科学版)》 CAS CSCD 北大核心 2007年第B06期248-249,共2页 Journal of Sun Yat-Sen University:Medical Sciences
  • 相关文献

参考文献4

  • 1李筱芳,刘维达.外阴阴道念珠菌病治疗的研究进展[J].国外医学(皮肤性病学分册),2004,30(4):205-208. 被引量:11
  • 2PIROTTA M, GUNN J, CHONDROS P, et al. Effect of lactobacillus in preventing post-antibiotic vulvovaginal candidiasis: a randomised controlled trial[J]. BMJ, 2004, 329 (7465):548.
  • 3MORAES P S, DE LIMA GOIABA S, TAKETOMI E A. Candida albicans allergen immunotherapy in recurrent vaginal candidiasis[J]. J Investig Allergol Clin Immunol, 2000,10(5): 305-309.
  • 4PIROTTA M, GUNN J, CHONDROS P, et al. Effect of lactobacillus in preventing post -antibiotic vulvovaginal candidiasis: a randomised controlled trial [J]. BMJ, 2004, 329 (7465):548.

二级参考文献20

  • 1Stevens DA, Calderon L, Martinez M, et al. Zeamatin, clotrimazole and nikkomycin Z in therapy of a Candida vaginitis model. J Antimicrob Chemother, 2002, 50:36l - 364.
  • 2Spinillo A, Colonna L, Piazzi G, et al. Managing recurrent vulvovaginal candidiasis. Intermittent prevention with itraconazole. J Reprod Med, 1997, 42:83 - 87.
  • 3Clemons KV, Stevens DA. Efficacy of ravuconazole in treatment of mucosal candidosis in SCID mice. Antimicrob Agents Chemother,2001,45:3433 - 3436.
  • 4Lass-Florl C, Dierich MP, Fuchs D,et al. Antifungal activity against Candida species of the selective serotonin-reuptake inhibitor, sertraline. Clin Infect Dis, 2001,33 :E135 - 136.
  • 5Altamura M, Casale D, Pepe M,et al. Immune responses to fungal infections and therapeutic implications. Curt Drug Targets Immune Endocr Metabol Disord, 2001, 1:189 - 197.
  • 6Dellenbach P, Thomas JL, Guerin V, et al. Topical treatment of vaginal candidosis with sertaconazole and econazole sustained-release suppositories. Int J Gynaecol Obstet, 2000, 71 :S47 - 52.
  • 7No authors listed. Management of genital candidiasis. Working Group of the British Society for Medical Mycology. BMJ, 1995, 310:1241 -1244.
  • 8Kubota T. Chronic and recurrent vulvovaginal candidiasis. Nippon Ishinkin Gakkai Zasshi, 1998, 39:213 - 218.
  • 9Ozyurt E, Toykuliyeva MB, Danilyans IL, et al. Efficacy of 7 -day treatment with metronidazole + miconazole (Neo-Penotran) - a tripleactive pessary for the treatment of single and mixed vaginal infections.Int J Gynaecol Obstet, 2001,74:35 - 43.
  • 10Martinez A, Ferrer S, Santos 1, et al. Antifungal activities of two new azasordarins, GW471552 and GW471558, in experimental models of oral and vulvovaginal candidiasis in immunosuppressed rats. Antimicrob Agents Chemother, 2001,45:3304 -3309.

共引文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部