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生长抑素(施他宁)在结直肠术后早期炎性肠梗阻治疗中的应用 被引量:16

Application of somatostatin in early postoperative inflammatory small bowel obstruction after colectomy
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摘要 目的:探讨生长抑素(施他宁)在结直肠术后早期炎性肠梗阻治疗中的作用。方法:将2002年2月至2006年10月期间29例结直肠术后早期炎性肠梗阻患者,随机分为生长抑素加常规治疗组(治疗组,15例)和常规治疗组(对照组,14例),观察两组病例治疗前后临床症状、体征、胃肠减压量、腹部平片、腹部CT、实验室检查及明确肠梗阻后的平均住院时间等各项指标,对结果分别进行对比。结果:治疗组肛门排气时间、腹胀症状消失时间较对照组提前,胃肠引流量减少,红细胞比容接近正常,平均住院时间明显缩短,两组患者的影像学检查均得到改善。结论:生长抑素能抑制消化道内液分泌,减轻肠壁水肿,缓解扩张,促进肠蠕动,对治疗结直肠术后早期炎性肠梗阻有明显作用。 Objective: To explore the effects of somatostatin in the treatment of early postoperative inflammatory small bowel obstruction after colectomy. Methods: From February 2002 to October 2006, 29 patients with early postoperative inflammatory small bowel obstruction after colectomy were randomly divided into experimental group (somatostatin therapy group, 15 cases) and control group (routine therapy group, 14 cases). Clinical symptoms, objective sign, naso-gastric tube decompression amounts, plain abdominal radiograph, abdominal CT, laboratory tests and mean hospital stay after onset of obstruction were observed and compared. Results: Imageology examination finding of the two groups were all improved. Anal discharging gas time, mean hospital stay after onset of obstruction and time of abdominal distention disappeared of experimental group was shorter than that of control group. The naso-gastric tube decompression amounts were reduced, and erythrocrits approached to normal in experimental group. Conclusion: Somatostatin has good effects on patients with early postoperative inflammatory small bowel obstruction after colectomy.
出处 《结直肠肛门外科》 2007年第5期291-293,共3页 Journal of Colorectal & Anal Surgery
关键词 术后早期炎性肠梗阻 生长抑素 治疗 Early postoperative inflammatory small bowel obstruction Somatostatin Therapy
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