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缬沙坦对兔动脉成形术后血管内膜增生及内皮细胞血管性假血友病因子表达的影响 被引量:2

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摘要 经皮冠状动脉介入治疗(PCI)已成为冠心病治疗的主要手段之一。PCI造成血管内皮剥脱,剥脱后邻近的内皮细胞向该区域移行、增殖,以初步覆盖剥脱区。达到再内皮化,剥脱区内皮的修复程度与再狭窄形成密切相关。内皮细胞损伤的面积决定新生内膜的增厚程度,损伤后内皮层再生速度的快慢对新生内膜增厚程度起着关键作用。本研究通过观察缬沙坦对兔腹主动脉球囊成形术后血管内膜增殖和内皮细胞血管性假血友病因子(vWF)表达的影响,以期进一步探讨Ⅰ型血管紧张素Ⅱ受体(AT1R)拮抗剂治疗血管再狭窄的机制。
出处 《中国危重病急救医学》 CAS CSCD 北大核心 2007年第11期695-696,I0002,共3页 Chinese Critical Care Medicine
基金 江苏省南通市社会发展科技计划项目(S40012)
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参考文献8

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共引文献19

同被引文献28

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