摘要
目的 :观察生脉注射液对全身炎症反应综合征患者血管活性介质的影响。方法 :33例全身炎症反应综合征患者随机分为西医常规治疗组 (15例 )和生脉注射液加常规治疗组 (18例 )。对两组患者治疗前后的血中前列环素 (PGI2 )、血栓素 A2 (TXA2 )、心钠素 (ANP)和内皮素 (ET)等进行自身比较及组间对照比较。结果 :治疗后生脉注射液治疗组患者血中 PGI2 、PGI2 /TXA2 较常规治疗组患者有一定程度的升高 ,TXA2 、ANP、ET水平降低 ,组间比较均存在显著性差异 (P<0 .0 5或 P<0 .0 1)。结论 :采用生脉注射液结合常规西医治疗 ,在一定程度上能够改善机体微循环 ,对保护脏器功能 ,防止全身炎症反应综合征的进一步发生、发展有一定的积极作用。
Objective: To observe the treatment effects of Shengmai injection(生脉注射液)on vasoactive mediator in patients with systemic inflammatory response syndrome(SIRS).Methods: Thirtythree cases with SIRS were randomly divided into two groups, 15 cases were treated with conventional therapy and 18 cases were treated with conventional therapy combined with Shengmai injection. The plasma levels of prostaglandin I_2(PGI_2), thromboxane A_2(TXA_2), arterial natriuretic polypeptide(ANP) and endothelin(ET) were compared before and after treatment in each group and between two groups. Results: Shengmai injection had marked (effects) on modulating the levels of vasoactive mediators. The plasma PGI_2 and PGI_2/TXA_2 elevated (significantly) after the Shengmai injection treatment, and plasma TXA_2, ANP and ET contents lowered. The (differences) were significantly between the two groups(all P<0.05). Conclusion: It suggests that (Shengmai) (injection) combined with conventional western medicine therapy could improve microcirculation, protect (organ's) (function). It has the effects in preventing SIRS and it may show us a new way to treat the SIRS.
出处
《中国中西医结合急救杂志》
CAS
2004年第4期239-241,共3页
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
关键词
生脉注射液
全身炎症反应综合征
血管活性介质
炎性介质
Shengmai injection
systemic inflammatory response syndrome
vasoactive mediator
(inflammatory) mediator
