摘要
1名43岁女性患者接受2%利多卡因3ml口腔局部麻醉,2min后出现头晕、恶心,继而意识丧失,面色苍白,出汗,呼吸急促,口唇发绀,心率145次/min,血压测未及,经肾上腺素、多巴胺、氟美松及快速补液处理后,患者意识恢复,血压、心率正常。然而2h后患者又出现呼吸困难、端坐呼吸、咯粉红色泡沫样痰,吸氧5L/min时指端SpO2降至0.78,BP升至180/110mmHg,HR140次/min,双肺内可闻及广泛的水泡音和哮鸣音,经给予硝普钠、毛花苷丙和呋塞米治疗后,上述症状消失。
A 43-year-old woman received 2% lidocaine solution 3 ml for local oral anesthesia. Two minutes later, she developed dizziness and nausea, and then progressed to unconsciousness, pale, sweating, short of breath, and cyanosis of the lips. Her heart rate was 145 beats/min, and her blood pressure was undetected. After treatment with epinephrine, dopamine, dexamethasone, and rapid fluid resuscitation, the patient＇s consciousness recovered and her blood pressure and heart rate returned to normal limits. However, 2 hours later, the patient developed dyspnoea, orthopnea, coughing up pink frothy sputum. Her finger tip pulse oxygen saturation （ SpO2 ） decreased to 0.78 during inhalation of oxygen 5 L/min. Her blood pressure increased to 180/110 mmHg, and heart rate was 140 beats/min. Extensive rales and wheezes in the lungs were heard. After receiving nitroprusside sodium, lanatoside C, and furosemide therapy, the patient＇s symptoms disappeared.
出处
《药物不良反应杂志》
2007年第5期363-364,共2页
Adverse Drug Reactions Journal
