摘要
目的探讨白细胞变形能力（ＬＤ）和白细胞粘附功能（ＬＡＦ）与冠心病（ＣＨＤ）发病的关系。方法采用红细胞变形能力测定仪和血栓血小板粘附两用仪，检测４２例健康老年人和９２例老年ＣＨＤ患者白细胞滤过指数（ＩＦ）和白细胞粘附率（ＬＡＲ）早晚动态变化。结果两组中，ＩＦ和ＬＡＲ早晨较下午高（Ｐ＜００５及００１）；ＣＨＤ患者ＩＦ和ＬＡＲ较对照组明显增高（Ｐ＜００１），且以急性心肌梗死（ＡＭＩ）患者变化最明显。结论ＣＨＤ发病早晨高发现象与ＬＤ和ＬＡＦ动态变化有密切关系。
Objective The diurnal variatons of leukocyte deformability (LD) and leukocyte addhesion function (LAF) were measured in patients with coronary heart disease (CHD) to study the correlation of the attacks of CHD with Ld and LAF. Methods Using erythrocyte deformability apparatus, thrombus and platelet adhesion dual purpose apparatus were used to measure the diurnal variation of lekocyte filtration index (IF) and leukocyte adhesion rate (LAR) in 42 healthy aged and 92 aged with CHD. Results The leukocyte IF and LAR in patients and controls were significantly higher in the morning than in the afternoon (P<0.05,0.04). The leukocyte IF and LAR were significantly higher in CHD patients than those in controls (P 0.01), and the variations in acute myocardial infarction (AMI) were the most obvious.\ \ Conclusions These results indicate that the phenomenon of the frequent ccurrence of attacks of CHD in the morning might be related to the diurnal variation of LD and LAF.
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
1997年第3期153-155,共3页
Chinese Journal of Geriatrics
