摘要
目的探讨B超诊断华支睾吸虫感染的临床应用价值。方法采用改良醛醚法检查粪便虫卵、ELISA法测定血清抗体,对经B超检查疑为华支睾吸虫感染的就诊者进行调查测定。结果实验室检测B超怀疑者269例,检获虫卵和(或)检出抗体146例,阳性率为54.3%。男性检测阳性率60.2%(130/216),女性30.2%(16/53)。有食鱼生史者(58.5%)捡出率高于无食鱼生史者(33.3%),但无统计学意义。对164例进行虫卵及抗体两项检测,虫卵及抗体均未检获(双阴性)者61例(37.2%)。认为,当前B超检查华支睾吸虫感染仍存在较高假阳性率。结论B超诊断华支睾吸虫病假阳性率很高,作为一项诊断技术有待完善和改进。
Objective To explore the clinical value of B ultrasound on diagnosing Clonorchis sinensis (C. sinensis) infection. Methods Feces and sera were collected from cases suspected by B ultrasound and the fecal examination was conducted by modified formalin ether sedimentation and sera were tested by ELISA. Results The lab examination indicated that 146 positives who have positive of the egg or the antibody were found from 269 cases accounting for 54.3% of all cases discredited by B ultrasound. The positive rate in male and female was 60.2%(130/216) and 30.2%(16/53). While the cases who had the history with raw fish showed higher positive rate but there was no significant difference comparing with the cases who had no history with raw fish. The negative rate of the egg and the antibody in the discredited cases was 37.2%, which means that the false positive was high while diagnosing with clonorchiasis by B ultrasound. Conclusion The study reveals that the false positive rate was higher when C. sinensis was diagnosed by B ultrasound and a technique of diagnosing C. sinensis it as will awaited to be improved and enhanced.
出处
《热带病与寄生虫学》
2006年第3期167-169,共3页
Journal of Tropical Diseases and Parasitology
关键词
华支睾吸虫
B超诊断
病原学诊断
效果评价
Clonorchis sinensis, Diagnosis by B ultrasound, Pathogenic diagnosis, Estimation of clinical value