摘要
目的探讨老年人戊型病毒性肝炎（以下简称戊肝）的临床特点。方法对老年人戊肝３０例及非老年人戊肝２２例作对照分析。结果在戊肝中，老年患者占２６５％。戊肝在急性病毒性肝炎中所占比例老年人明显高于非老年人（分别为４２９％及１７２％，Ｐ＜００１）。老年人戊肝发热少见，淤胆症状常见，起病缓慢；血清丙氨酸氨基转移酶（ＳＡＬＴ）升高值较低，血清胆红素升高值更高，复常时间更长。结论老年人戊肝不少见，其临床特点为起病缓慢，易发生淤胆，以黄疸型为主，且黄疸程度重，持续时间长，重型患病率不高，预后较好。
Objective Viral hepatitis E in elderly has been reported rarely.This study analyzedmainly its clinical features. Methods There were 30senile cases with viral hepatitis E admitt edfrom September 1992 to July 1995.This senile group was compared with a non senile group with viralhepatitis Eadmitted in the same period.The serum antibodies against viral hepatitis Ewere positive in all patients,meanwhile the infections of viral hepatitis A,B,C,Epstein Barr virus and cy tomegalovirus were excluded.The serum alanine aminotransferase,bilirub in and albumin were examined on admission and every two weeks afterwards. Results The proportion of viral hepatitis E in senile cases with acute viral hepatitis was obviously higher than in non senile group(P<0 01).Insenile cases with viral hepatitis E,fever was rare,cholestasis was more common and onset was insidious.Moreover,elevation of alanine aminotransferase was less,jaundice was more marked with a higher serum bilirubin level and longer duration. Conclusions The viral hepatitis E is often seen in the elderly with acute viral hepatitis.The senile cases with viral hepatitis have the following clinicalfetaures:onset insidious,cholestasis common,jaundice severe and long lasting,but the incidence of grave viral hepatitis is not high and the prognosis is good.
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
1997年第3期144-146,共3页
Chinese Journal of Geriatrics
