摘要
目的了解近5年来南京地区散发性急性戊型肝炎的发病情况。方法对2001年1月至2005年12月我院收治的311例散发性急性病毒性肝炎患者采用ELISA方法检测血清抗-HAV-IgM、HBVM、抗-HCV、抗-HEV IgM/IgG,对其中的戊型肝炎进行流行病学分析。结果311例散发性急性病毒性肝炎中,戊型肝炎占54.98%(171/311),甲型肝炎、乙型肝炎、丙型肝炎分别占15.11%(47/311)、28.94%(90/311)、0.96%(3/311)。2001-2005年戊型肝炎分别占散发性急性肝炎的26.92%、33.33%、54.69%、75.32%和70.15%。12月份至次年5月份戊型肝炎发病人数占戊型肝炎总病例数的78.36%。戊型肝炎中50岁以上患者所占比例显著高于甲型肝炎和急性乙型肝炎(χ2=16.78、χ2=16.97,P均<0.01),戊型肝炎男女性别比与甲型肝炎和乙型肝炎比较均无显著性差异(χ2=0.003、χ2=0.098,P均>0.05)。结论近5年来,南京地区散发性急性病毒性肝炎中戊型肝炎居首位,发病人数呈明显上升趋势。戊型肝炎发病呈明显的季节、年龄及性别分布。对戊型肝炎的预防应当引起高度重视。
Objective To investigate the incidence of sporadic acute viral hepatitis E （HE） in the recent five years in Nanjing area. Methods Serum anti-HAV IgM,HBVM,anti-HCV and anti-HEV IgM/IgG,were detected with ELISA methods in 311 cases of sporadic acute viral hepatitis,and the epidemiologic features of hepatitis E were further analyzed. Results Of the 311 sporadic acute viral hepatitis,HE,HA,HB,HC occupied 54.98%,15.11%,28.94%,0.96% ,respectively. The proportion of HE From 2001 to 2005 were 26.92%,33.33%,54.69%,75.32% and 70.15%,respectively. Among 171 HE cases, 78.36% occurred between December to May. The proportion of over 50 years old in HE cases was higher than those in HA and HB cases（X^2= 16.78,P〈 0.01 ;X^2= 16.97,P〈0.01）. No singificant difference was found in the ratio of male to female between HE and HA or HB cases （X^2 =0. 003,P〉0.05;X^2=0. 098,P〉0.05）. Conclusion HE has the highest proportion among 311 patients with sporadic acute viral hepatitis in Nanjing area from 2001 to 2005 and the incidence of HE shows a increasing trend. The sporadic acute HE presents season ,age and sex distribution features.
出处
《东南国防医药》
2007年第2期102-104,共3页
Military Medical Journal of Southeast China
关键词
肝炎
散发性
急性
戊型肝炎
Hepatitis
Sporadic
Acute
Hepatitis E
