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CVD方案治疗晚期恶性黑色素瘤28例 被引量:1

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摘要 目的:探讨晚期恶性黑色素瘤用CVD方案治疗的疗效与毒副作用。方法:28例晚期恶性黑色素瘤患者接受CVD方案联合化疗,总治疗周期数为124个。结果:28例中完全缓解2例,部分缓解8例,有效率36%,主要毒副反应为血液学毒性和胃肠道反应,没有因毒副反应而停药的病例。结论:CVD方案对晚期恶性黑色素瘤有一定疗效,毒副反应能耐受,可作为晚期恶性黑色素的有效治疗方案。
出处 《实用医学杂志》 CAS 2007年第21期3439-3440,共2页 The Journal of Practical Medicine
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  • 1王东霞,李先明.恶性黑色素瘤脑转移的治疗进展[J].实用医学杂志,2006,22(4):479-480. 被引量:5
  • 2Legha S S, Ring S, Papadoponlos N, et al. A prospective evaluation of a triple-drug regimen containing cisplatin, vinblastine, and dacarbazine (CVD) for metastatic melanoma [J]. Cancer, 1989,64 (10) : 2024-2029.
  • 3Margolin K ,Atkins M ,Sparano J ,et al. Prospective randomized trial of lisofylline for the prevention of toxicities of high-dose interleukin 2 therapy in advanced renal cancer and malignant melanoma [J]. Clin Cancer Res, 1997, 3(4) :565-572.
  • 4Keilholz V, Conradt C, Legha S S, et al. Results of interleukin-2- based treatment in advanced melanoma: a ease record-based analysis of 631 patients [J]. J Clin Oneol , 1998,16(9):2921-2929.
  • 5Allen I E, Knpelnick B, Komasshiro M, et al. Efficacy of interleukin-2 in the treatment of metastatic melanoma [J]. Cancer Ther, 1998, 1 : 168-173.
  • 6Eton O, Legha S S, Bedikian A Y, et al. Sequential biochemotherapy versus chemotherapy for metastatic melanoma: results from a phase Ⅲ randomized trial [J]. J Clin Oncol, 2002, 20(8) : 2045-2052.
  • 7Atkins M B, Lee S, Flaherty L E, et al. A prospective randomized phase Ⅲ trial of concurrent biochemotherapy (BCT) with cisplatin, Vinblastine, dacarbazine(CVD) ;IL-2 and interferon alpha-2b(IFN) versus CVD a;one in patients with metastatic melanoma (E 3695 ) : an ECOG-corrdinated in tergroup trial [J]. Proc Am Soc Clin Oncol, 2003, 22 : 708.
  • 8Keilholz U, Punt C J, Gore M, et al. Dacarbazine, cisplatin and IFN-α2b with or without IL-2 in advanced melanoma: Final analysis of EORTC randomized phase Ⅲ trial 18951 [J]. Proc Am Soc Clin Oncol, 2003,22 : 2848.
  • 9Keilholz U, Goey S H, Punt C J, et al. Interferon alfa-2a and interleukin-2 with or without cisplatin in metastatic melanoma:a randomized trial of the European Organization for Research and Treatment of Cancer Melanoma Cooperative Group [J]. J Clin Oncol, 1997, 15(7):2579-2588.
  • 10Rosenberg S A, Yang J C, Schwartzentruber D J, et al. Prospective randomized trial of the treatment of patients with metastatic melanoma using chemotherapy with cisplatin, dacarbazine, and tamoxifen alone or in combination with interleukin-2 and interferon alfa-2b [J]. J Clin Oncol , 1999, 17(3):968-975.

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