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西宁地区充血性心衰患者血浆一氧化氮的变化及临床意义

The Change and Its Significance of Plasma Level of Nitric Oxide in Patients with Congestive Heart Failure in Moderate Altitude Area
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摘要 目的:分析西宁地区充血性心力衰竭(CHF)一氧化氮(NO)的含量变化及其临床意义。方法:检测59例临床确诊为CHF的患者血浆NO含量,另选31例健康体检者作为正常对照组。结果:西宁地区CHF患者血浆NO水平明显高于对照组(P<0.01),且心衰程度越重,NO水平越高。结论:血浆NO可作为反映CHF严重程度的客观指标之一,且在CHF病理生理改变中起重要作用。 Objective:To investigate the change and the clinical significance of plasma nitric Oxide (NO) in patients with congestive heart failure(CHF) in moderate area. Methods. Plasma level of NO was measured in 59 patients with CHF and 41 healthy subjects served as normal controls. Results: The plasma level of NO was significantly higher in patients with CHF than in controls (P〈0. 01) and in which the level of plasma NO was significantly higher in NYHA functional class Ⅱ-Ⅳ. Conclusions: The plasma level of NO can be used as a degree parameter of CHF; NO plays an important rote in pathophysiology of CHF.
出处 《高原医学杂志》 CAS 2007年第3期35-37,共3页 Journal of High Altitude Medicine
基金 青海省科技厅自然科学基金项目(编号2006-N-149)部分研究内容
关键词 充血性心力衰竭 一氧化氮 西宁地区 Congestive heart failure Nitric oxide High altitude
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参考文献9

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