摘要
目的探讨内镜治疗慢性胰腺炎(CP)的治疗效果。方法研究自1997年1月至2004年12月期间在上海长海医院确诊为 CP,并住院行内镜治疗的患者,随访观察其临床疗效。结果符合 CP 诊断标准并进行内镜下治疗的患者共296例。其中胰管括约肌单纯切开23例,胰头部胰管气囊扩张11例,胰管取石86例。138例放置主胰管支架,26例放置副胰管支架。EUS 下经胃壁假性囊肿引流12例,EUS 下腹腔神经节阻滞30例。224例患者腹痛症状均有不同程度缓解(P<0.05),1周后148例患者腹痛症状缓解,其中34例(15.2%)腹痛缓解持续时间达7年。患者内镜治疗成功率100%,无严重并发症发生,体质量均有一定程度增加(P<0.05)结论内镜治疗能有效缓解 CP 患者的腹痛症状,增加患者的体质量,是治疗 CP 的一种安全有效的手段。
Objective To explore the therapeutic effect of endoscopic therapy in chronic pancretitis. Methods All patients matched with chronic pancreatitis and treated by endoscopy in Changhai hospital from January 1997 to July 2004 were recruited in the study. All patients were follow-up for 1 week to 7 years. Results There were 296 patients involved in the study. Of the total, simply sphincterotomy of pancreatic sphincter was 23 （7.77%）, dilated by the bladder in the proximal end of the pancreatic duct was 11 （3. 71% ）; 86（29.05%） patients had the clearance of stone. 138 patients had placement of pancreatic stent in the main pancreatic duct, and 26 in accessory pancreatic duct. The pain was relieved totally or partially in 224 patients（ P 〈0. 05 ）. The pain were palliated in 148 patients after lw, there was 34 patients who had persistent pain for 7y. The body weight of all the patients had increased. Before management the BMI was 14. 8 ～30. 0（20. 3±2.4） and 12.9～78.0（28.0 ± 15.9） after 1 year. Because of persistent pain, 12 stents were dislodged after 28 d or 45 d, the other 126 patients has stents in body for 6m （ stent was exchanged every 2 or 3 months）. The achievement of the management was 100%, after management, 3 patients had vomiting, there was hyperamylasemia in 31 patients in 24h; stents failed off in 3 patients and migrated in 6 patients. Conclusion Endo-therapy of chronic pancreatitis can relieved pain effectively and can increase body weight. Pancreatic stent therapy has low incidence of complication.
出处
《中华消化内镜杂志》
2007年第5期338-341,共4页
Chinese Journal of Digestive Endoscopy
关键词
胰腺炎
慢性
胰胆管造影术
内窥镜逆行
治疗效果
Pancreatits, chronic
Cholangiopancreatography, endoscopic retrograde
Treatmentoutcome
