期刊文献+

卡介菌多糖核酸治疗面部糖皮质激素依赖性皮炎疗效观察 被引量:1

Effect of BCG Polysaccharide Nucleic Acid on Patients with Facial Corticosteroid Dependent Dermatitis
暂未订购
导出
摘要 目的观察卡介菌多糖核酸对面部糖皮质激素(以下简称激素)依赖性皮炎的临床疗效。方法将42例患者随机分为2组,对照组:内服西替利嗪或氯雷他定、硼酸溶液冷湿敷、外用炉甘石洗剂和单霜;治疗组:在对照组的基础上注射卡介菌多糖核酸2ml,隔日1次,共12周,于治疗后4,8,12周评价疗效。结果治疗组总有效率71.43%,明显高于对照组的33.33%(P<0.01)。结论卡介菌多糖核酸治疗面部糖皮质激素依赖性皮炎有较好的疗效。 Objective To investigate the effect of BCG polysaccharide nucleic acid (BCG-PSN) on patients with facial steroid corticosteroid dependent dermatitis, Methods 42 patients were divided into 2 groups randomly. The subjects in control group were treated with antihistamine. The subjects in the treatment group were added BCG-PSN. Therapeutic effect was observed after 12 weeks. The clinical symptom and sign scores were records before and after treatment. Results In the treatment group,curative efficiency was 71,43 %, In the control group, efficacy rate was 33.33 %, The difference between the two groups was significant (P 〈0.01 ). Conclusions BCG polysaccharide nucleic acid is effective for the patients with facial corticosteroid dependent dermatitis.
作者 张丽萍 孙鸿
出处 《实用全科医学》 2007年第11期958-959,共2页 Applied Journal Of General Practice
关键词 卡介菌多糖核酸 面部糖皮质激素依赖性皮炎 BCG polysaccharide nucleic acid Facial corticosteroid dependent dermatitis
  • 相关文献

参考文献4

二级参考文献17

  • 1杨磊,苏敬泽.外用皮质类固醇激素引起的反跳现象120例临床观察[J].临床皮肤科杂志,1996,25(4):233-234. 被引量:7
  • 2Portales P, Aries MF, Licu D, et al. Immunomodulation induced by Avene spring water on Th1 and Th2-dependent cytokine production in healthy subjects and atopic dermatitis patients[ J ]. Skin Pharmacol Appl Skin Physiol,2001,14(4) :234 -242.
  • 3Thomas B, Kenneth A, Wallace H,et al.Dermatology in general medicine[M].New York: Mcgraw-Hill, 1971.297-386.
  • 4Rapaport MJ,Rapaport V.Eyelid dermatitis to red face syndrome to cure:clinical experience in 100 cases[J].J Am Acad Dermatol,1999,41(3 Pt 1):435-442.
  • 5Ljubojeviae S,Basta-Juzbasiae A,Lipozeneiae J.Steroid dermatitis resembling rosacea:aetiopathogenesis and treatment[J].J Eur Acad Dermatol Venereol,2002,16(2):121-126.
  • 6陆洪光.面部激素依赖性皮炎[G]//中华医学会.2003年全国皮肤性病学术年会论文汇编.上海:[出版者不详].2003:7.
  • 7Antille C,Saurat JH,Lubbe J.Induction of rosaceiform dermatitis during treatment of facial inflammatory dermatoses with tacrolimus ointment[J].Arch Dermatol,2004,140(4):457-460.
  • 8Amerio P,Frezzolini A,Feliciani C,et al.Eotaxins and CCR3 receptor in inflammatory and allergic skin diseases:therapeutical implications.Curr Drug Targets Inflamm Allergy,2003,2:81-94.
  • 9Mattes J,Foster PS.Regulation of eosinophil migration and Th2cell function by IL-5 and eotaxin.Curr Drug Targets Inflamm Allergy,2003,2:169-174.
  • 10Sallusto F,Mackay CR,Lanzavecchia A.Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells.Science,1997,277:2005-2007.

共引文献303

同被引文献9

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部