摘要
检测原发性肺癌４８例的抗凝血酶Ⅲ活性（ＡＴ－Ⅲ：Ａ）、抗凝血酶Ⅲ抗原（ＡＴ－Ⅲ：Ａｇ）、ａ＿２巨球蛋白（α＿２－ＭＧ）、血浆纤溶酶原活性（Ｐｌｇ：Ａ）、血浆纤溶激活活性（ＦＡＡ）．血浆纤溶激活抑制活性（ＦＩＡ）、组织型纤溶酶原激活物（ｔ－ＰＡ）及其抑制物（ＰＡＩ）。结果表明，肺癌患者抗凝活性较正常人显著降低而纤溶活性增强，血液抗凝与纤溶状态异常与肿瘤期别有关，α＿２－巨球蛋白有突出的变化。
Eight parameters related to anticoagulant and fibrinolytic state included antith.nmbin Ⅲactivity ( AT- Ⅲ, A ) , antithrombin Ⅲantigen ( AT- Ⅲ, Ag ) , Macroglobulin (α-MC) ,plasminogen activity (plg , A ) , fibrinolysis activating activity (FAA) , fihrinolysis activating-inhibiting activity (FIA) , tissue-type plasminogen activator (t-PA ) and inhihitors of plasminogen activator(PAI ) were studied on fourty-eight patients with primary lung cancer. The parameters were compared according to the different histological types and TNM stages. Results showed that ( 1 ) the anticoagulant actitity in the patients with lung cancer was significantly lower than that in healthy controls;( 2 ) fibrinolytic activity in the patients was enhanced : ( 3 ) the abnornnal anticoagulant and fibrinolytic state existed in the lung cancer pa tients was associa ted wi th the TNM stages of pu lmonary neoplasm ; ( 4 ) there was a prominent change of α-MG in the plasma of the patients.
出处
《山东医科大学学报》
1997年第2期142-144,共3页
Acta Academiae Medicinae Shandong
