摘要
研究无创性磁共振冠状动脉造影（ＭＲＣＡ）技术的可行性及其在冠状动脉疾病诊断中的价值。方法对１２例健康志愿者和２１例近期接受诊断性Ｘ线冠状动脉造影（ＸＣＡ）的病人进行了ＭＲ－ＣＡ成像。结果３３例受检者均顺利完成检查。右冠状动脉、左主干、左前降支、左旋支的显示率分别为９７％、１００％、９１％和９１％；显示长度分别为５１±１５（２８～８０）ｍｍ，１１±４（４～２２）ｍｍ，４４±１３（２４～６６）ｍｍ和４０±１２（２０～６６）ｍｍ。２１例有ＸＣＡ对比的病人中，３７处近、中段血管狭窄中有２９处（７８％）可被ＭＲＣＡ识别。结论ＭＲＣＡ可识别左右冠状动脉近段４～５ｃｍ内的大部分中度以上狭窄病变，对轻度狭窄不够敏感，远端血管狭窄尚不能显示。目前可作为一项补充性的冠状动脉成像方法有选择地试用于临床。
Objective To assess the ability of imaging coronary arteries noninvasively with magnetic resonance angiography technique (MRCA) and its diagnostic value in coronary artery disease. Methods MRCA was performed on 33 subjects, including 12 healthy adult volunteers and 21 patients with available recent X ray contrast angiography (XCA) results. MRCA technique consisted of a gradient echo sequence (Turbo Cine), two dimensional acquisition, fat suppression, peripheral gating. Subjects were imaged in supine position using a standard body coil, without breath hold. Results All 33 subjects were imaged successfully. Identification of the coronary artery was possible for the right coronary, left main stem, left anterior, and left circumflex arteries respectively in 97%, 100%, 91% and 91% with a visualized mean length of 51±15(28～80 mm),11±4(4～22 mm), 44±13(24～66 mm), 40±12(20～66mm). In the 21 subjects with available XCA results, 78% (29/37) proximal stenoses of the coronary arteries were detected with MRCA. Conclusion At current stage, MRCA can depict most of the hemodynamically significant proximal stenoses but not the distals. This procedure can be used as an alternative imaging application under certain clinical indications.
出处
《中华医学杂志》
CAS
CSCD
北大核心
1997年第7期521-524,共4页
National Medical Journal of China
关键词
血管造影
冠状动脉
NMR
Magnetic resonance Angiography Coronary artery
