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TGF-β基因与非综合征性唇腭裂相关性研究进展 被引量：3

TGF-β gene and nonsydromic cleft of lip with or without palate
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摘要 唇腭裂是口腔颌面部最常见的一种先天性发育畸形，在新生儿的发生率因人种、民族和地区而异，约为1／10001／500，占所有先天性畸形的65％左右，在我国发生率约为1．82‰。非综合征性唇腭裂（nonsydromic cleft of lip with or without palate，NSCL／P）是指单发的唇裂、腭裂或唇裂合并腭裂，占唇腭裂的70％以上，它是一种排除了其他系统畸形和综合征的唇腭裂，
作者 刘宁 万伟东
机构地区 东南大学附属中大医院整形外科
出处 《中国美容医学》 CAS 2007年第10期1445-1447,共3页 Chinese Journal of Aesthetic Medicine
基金 江苏省卫生厅医学科技发展基金(编号:H200513)
关键词 非综合征性唇腭裂 先天性发育畸形 TGF 唇裂合并腭裂 基因 口腔颌面部 先天性畸形 发生率
分类号 R782.21 [医药卫生—口腔医学]
  • 相关文献

参考文献22

  • 1Slavkin HC.Congenital craniofacial malformations:indentifying individuals at risk[J].Ear No se Th roat J,1979,58(1):7-20.
  • 2Carinci F,Pezzetti F,Scapoli L,et al.Recent developments in orofacial cleft genetics[J].J Craniofac Surg,2003,14(2):130-143.
  • 3Davies AF,Stephens RJ,Olavesen MG,et al.Evidence of a locus for orofacial clefting on human chromosome 6p24 and STS content map of the region[J].Hum Mol Genet,1995,4(1):121-128.
  • 4静广平,焦晓辉.家族性非综合征性唇裂伴或不伴腭裂的基因研究[J].口腔医学研究,2004,20(2):216-218. 被引量：5
  • 5焦晓辉,王丽,徐旭光.中国人群非综合征性唇腭裂与TGFβ3多态性的关系[J].哈尔滨医科大学学报,2003,37(5):415-418. 被引量：19
  • 6Boesen CC,Radaev S,Motyka SA,et al.The 1.1 A crystal structure of human TGF-beta type Ⅱ receptor ligand binding domain[J].Structure,2002,10(7):913-919.
  • 7Shull MM,Ormsby I,Kier AB,et al.Targeted disruption of the mouse transforming growth factor-β 1 gene results in multifocal inflammatory disease[J].Nature,1992,359:693-699.
  • 8Kinoshita A,Saito T,Tomita H,et al.Domain-specific mutations in TGFB 1 result in Camurati-Engelmann disease[J].Nat Genet,2000,26:19-20.
  • 9Barton DE,Foellmer BE,Du J,et al.Chromosomal mapping of genes for transforming growth factors beta-2 and beta-3 in man and mouse:dispersion of TGF-beta gene family[J].Oncogene Res,1988,3:323-331.
  • 10Kaartinen V,Voncken JW,Shuler C,et al.Abnormal lung development and cleft palate in mice lacking TGF-β 3 indicates defects of epithelial-mesenchymal interaction[J].Nat Genet,1995,11:415-421.

二级参考文献64

  • 1房洪波,王蓓.唇腭裂患者1309例临床资料分析[J].实用口腔医学杂志,2004,20(4):502-503. 被引量：4
  • 2徐莉,B. G. Loos.牙槽骨吸收与吸烟状况的研究[J].实用口腔医学杂志,2005,21(2):157-159. 被引量：12
  • 3[1]Margaret E, Cooper MS. Descriptive epidemilolgy of nonsyndromic cleft lip with or without cleft palate in Shanghai, China, from 1980 to 1989. Cleft Palate-Carniofacial Journal, 2000, 37(3)∶274-280
  • 4[2]Lidral AC, Romitti PA, Basart AM. Association of MSX1 and TGFβ3 with nonsyndromic clefting in humans. Am J Hum Genet, 1998, 63(2)∶557-568
  • 5[3]Mitchell LE, Risch N. Correlates of genetic risk for non-syndromic cleft lip with or without cleft palate. Clin Genet, 1993,43(5)∶255-260
  • 6[4]Prescott NJ, Lees MM, Winter RM. Identification of susceptibility loci for nonsyndromic cleft lip with or without cleft palate in two stage genome scan of affected sib-pairs. Hum Genet, 2000,106(3)∶345-350
  • 7[5]Mary L, Marazita L, Leigh F, et al. Genome scan for loci involved in cleft lip with or without cleft palate, in China multiplex families. Am J Hum Genet, 2002,71(2)∶349-364
  • 8[6]Wong FK, Catharina H, Agneta K, et al.Linkage analysis of candidate region in Swedish nonsyndromic cleft lip with or without cleft palate families. Cleft Palate-Craniofacial Journal, July, 2000,37(4)∶357-362
  • 9[7]Farrall M, Holder S. Familial recurrence-pattern analysis of cleft lip with or without cleft palate. Am J Hum Genet, 1992,50(2)∶270-277
  • 10[8]Hetch JT, Wang YP, Blanton SH, et al. Cleft lip and palate:no evidence of linkage to transforming growth factor alpha. Am J Hum Genetics,1991,49(3)∶682-686

共引文献29

同被引文献41

  • 1吴镝,赵振民.非综合征型唇腭裂的病因学研究现状[J].中国美容医学,2006,15(11):1321-1323. 被引量：2
  • 2Prescott NJ,Winter RM,Malcolm S. Nonsyndromic cleft lip and palate: complex genetics and environmental effects [J].Ann Hum Genet,2001,65:505-515.
  • 3Carinci F,Scapoli L,Palmieri A,et al. Human genetic factors in nonsyndromic cleft lip and palate: An update [J]. hat J Pediatr Otorhinolaryngol,2007,71 : 1509-1519.
  • 4Vieira AR,McHenry TG,Marazita ML, et al. Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts[J].Genet Med,2008,10(9):668-674.
  • 5Knight AS,Schutte BC,Jiang R,et al. Developmental Expression Analysis of the Mouse and Chick Orthologues of IRF6: The Gene Mutated in Van Der Woude Syndrome [J]. Dev Dyn, 2006,235(5): 1441-1447.
  • 6Stanier P,Moore GE.Genetics of cleft lip and palate: syndromic genes contribute to the incidence of non-syndromic clefts [J]. Hum Mol Genet,2004,13:R73-81.
  • 7Forbes SA,Brennan L,Richardson M,et al. Refined mapping and YAC contig construction of the X-linked cleR palate and ankyloglossia locus (CPX) including the proximal X-Y homology breakpoint within Xq21.3 [J]. Genomics, 1996,31 ( 1):36-43.
  • 8Braybrook C,Doudney K,Marcano AC,et al.The T-box transcription factor gene TBX22 is mutated in X-linked clett palate and ankyloglossia[J]. Nat Genet,2001,29(2): 179-183.
  • 9Marcano AC,Doudney K,Braybrook C,et al.TBX22 mutations are a frequent cause of cleft palate[J]. Med Genet,2004,41:68-74.
  • 10Prescott NJ,Lees MM, Winter RM, et al. Identification of susceptibility loci for nonsyndromic cleft lip with or without cleft palate in a two stage genome scan of affected sib-pairs [J]. Hum Genet,2000,106:345-350.

引证文献3

二级引证文献12

中国美容医学
2007年 第10期

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