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苦豆子总碱对大鼠实验性结肠炎中调节性T细胞及Foxp3 mRNA的表达影响 被引量：2

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摘要 苦豆子是豆科槐属植物，主要成分为生物碱，有槐果碱、苦参碱、氧化苦参碱、槐定碱、槐胺碱等。药用根、根茎、全草及种子，味苦性寒，有清热解毒、祛风燥湿、止痛杀虫等作用，民间常用于菌痢、肠炎。本研究是在前期药效明确的基础上拟从分子免疫方面进一步探讨其在大鼠实验性结肠炎中的治疗作用及作用机制。
作者 周毅 邓虹珠 王赫 梁磊 赵文昌
机构地区 广州医学院药学系药理教研室 南方医科大学中医药学院
出处 《中华消化杂志》 CAS CSCD 北大核心 2007年第10期708-709,共2页 Chinese Journal of Digestion
关键词 实验性结肠炎 苦豆子总碱 调节性T细胞 FOXP3 mRNA 大鼠 氧化苦参碱 槐属植物
分类号 R285.5 [医药卫生—中药学]
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共引文献223

同被引文献19

  • 1朱庆强,王中秋.慢性炎症性肠病的影像学诊断及其进展[J].医学研究生学报,2011,24(8):883-887. 被引量：6
  • 2张琳娜,白洁.苦豆子药理作用的研究进展[J].宁夏医学院学报,2004,26(3):214-217. 被引量：24
  • 3张为民,张彦明,张涛,张德刚,廖小敏,张议允.苦豆子生物碱抑菌抗炎作用研究[J].动物医学进展,2005,26(10):82-85. 被引量：42
  • 4林萍,吴星宇,潘慧,胡胜娣,梅林.实验性结肠炎中移动抑制因子活性的神经调节[J].中国药理学通报,2007,23(5):577-581. 被引量：3
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中华消化杂志
2007年 第10期

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