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胃镜检查前抑酸疗法对胃癌漏诊影响的临床研究 被引量:2

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摘要 目的研究抑酸疗法对胃癌患者首次胃镜检查诊断的干扰程度及相应对策。方法研究对象均为经胃镜与病理检查最终证实的胃癌患者,包括胃体腺癌与胃窦腺癌。根据首次电子胃镜检查前抑酸剂[H2受体阻滞剂(H2RA)和质子泵抑制剂(PPI)]的使用情况,分为H2RA治疗组、PPI治疗组及对照组(未用抑酸疗法),比较各组的胃癌漏诊率。结果H2RA治疗组胃体腺癌和胃窦腺癌的漏诊率分别为6.67%和10.77%,PPI治疗组的漏诊率分别为9.43%和12.66%,均明显高于对照组(1.37%和2.63%)。漏诊患者以早期胃癌Ⅱc型及进展期胃癌Ⅱ型、Ⅲ型为主。结论抑酸疗法在胃镜检查前的不恰当应用,对某些胃癌的及时诊断产生负面影响,致使部分患者漏诊,甚至延误治疗。
作者 毛发明
出处 《中国医师进修杂志(内科版)》 2007年第11期55-56,共2页 Chinese Journal of Postgraduates of Medicine
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  • 1Yalamarthi S,Witherspoon P,McCole D,et al. Missed diagnoses in patients with upper gastrointestinal cancers. Endoscopy,2004,36 (10): 874-879.
  • 2Lassen A,Hallas J,de Muckadell OB,et al. First-time endoscopy and use of antisecretory medication: a population-based cohort study. Scand J Gastroenterol, 2005,40(6):705-712.
  • 3Suvakovic Z, Bramble M G,Jones R, et al. Improving the detection rate of early gastric cancer requires more than open access gastroscopy:a five year study.Gut, 1997,41 (3) : 308-313.
  • 4Bramble MG,Suvakovic Z,Hungin AP. Detection of upper gestrointestlnal cancer in patients taking antisecretory therapy prior to gastroscopy. Gut,2000,46(4) :464-467.
  • 5Wayman J,Hayes N,Grltrm SM,et aL The response of early gastric cancer to proton-pump inhibitors. N Engl J Med, 1998,338 (26) : 1924-1925.
  • 6Martin IG,Young S,Sue-Ling H,et al. Delays in the diagnosis of ossophagogastric cancer: a consecutive case series. BMJ,1997,314 (7079): 467-470.
  • 7Lassen A,Hallas J,de Muckadell OB,et aL The risk of missed gastroesophageal cancer diagnoses in users and nonusers of antisecretory medication. Gastroenterology, 2005,129(4) : 1179-1186.
  • 8Wayman J,Hayes N,Raimes SA,et al. Prescription of proton pump inhibitors before endoscopy. A potential cause of missed diagnosis of early gastric cancers. Arch Fain Med, 2000,9(4) : 385-388.

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