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男性急性冠状动脉综合征患者血浆脂联素水平及相关分析

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摘要 目的探讨男性急性冠状动脉综合征（ACS）患者血浆脂联素水平与冠状动脉粥样硬化病变程度的关系。方法64例男性ACS患者（ACS组），根据冠状动脉造影结果，按狭窄所累及的血管支数分为：单支血管病变组25例，双支血管病变组18例，三支血管病变组21例。另选择41例男性作为健康对照组。采用放射免疫方法检测血浆脂联素水平。结果ACS组血浆脂联素水平显著低于健康对照组，P〈0．01。三支血管病变组较单支血管病变组血浆脂联素水平降低（P〈0．05）。血浆脂联索水平与体重指数及三酰甘油呈负相关（P〈0．01）；而与高密度脂蛋白-胆固醇呈正相关（P〈0．01）。结论血浆脂联索水平与ACS发生相关，可能是判断冠状动脉病变严重程度的一个指标，可成为冠状动脉疾病发病的一个独立危险因素。
作者 胡鸿妍 吕田 姜涵
机构地区 大连医科大学附属第一医院特需医疗部
出处 《中国医师进修杂志（内科版）》 2007年第11期40-42,共3页 Chinese Journal of Postgraduates of Medicine
关键词 脂联索 危险因素 急性冠状动脉综合征
分类号 R543.3 [医药卫生—心血管疾病]
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参考文献8

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二级参考文献15

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共引文献13

中国医师进修杂志（内科版）
2007年 第11期

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