摘要
以自行合成的丝氨酸铜Cu（Ser）2和甘氨酰甘氨酸铜Cu（Gly-Gly）2作为SOD模拟物，在pH7．8及（20．0±0．5）℃条件下，用脉冲辐解法分别研究其催化超氧阴离子自由基（O）歧化反应的动力学，得到了反应级数n及催化速率常数kcat，并初步探讨了反应机理．证实了水溶液中Cu（Ⅱ）－氨基酸络合物催化O歧化反应乒乓机理中的第一步反应是整个反应过程的速控步骤．
Cu(Ser)2 and Cu(Gly-Gly)2, as analogues of SOD were prepared. Kinetics of dismutation of superoxide ion catalyzed by Cu(Ser)2 and Cu(Gly-Gly)2 by using pulse radiolysis were studied at PH 7.8 and (20.0±0.5)℃. The rate constants Kcat, the reaction order n were obtained and the catalyst mechanism was probed. The first step in the mechanism is the determined step was proved.
出处
《北京师范大学学报（自然科学版）》
CAS
CSCD
北大核心
1997年第2期226-230,共5页
Journal of Beijing Normal University(Natural Science)
基金
国家自然科学基金!29373092
关键词
超氧阴离子
自由基
催化
SOD
丝氨酮铜
歧化反应
superoxide ion(O_2
-)
Cu(Ⅱ)- amino add complexes
pulse radiolysis
dismutation mechanism
