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A Convenient Synthesis of 2-Arylnaphtho[1,2-d]oxazole Derivatives Promoted by Triethylamine

A Convenient Synthesis of 2-Arylnaphtho[1,2-d]oxazole Derivatives Promoted by Triethylamine
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摘要 A variety of 2-arylnaphtho[ 1,2-d]oxazole derivatives were efficiently synthesized in moderate to high yields by the reaction of aromatic aldehydes with 1-amino-2-naphthol derivatives in the presence of triethylamine in refluxing ethanol in air. Seven new 2-arylnaphtho[1,2-d]oxazole derivatives were obtained and characterized by the spectral data and elemental analysis. In addition, the X-ray crystal structures of 2-[4-(N,N-dimethylamino)phenyl]naphtho[ 1,2-d] oxzole (3d) and 1, 1'-bis(naphtho[ 1,2-d]oxazol-2-yl)ferrocene (3n) have been determined. A variety of 2-arylnaphtho[ 1,2-d]oxazole derivatives were efficiently synthesized in moderate to high yields by the reaction of aromatic aldehydes with 1-amino-2-naphthol derivatives in the presence of triethylamine in refluxing ethanol in air. Seven new 2-arylnaphtho[1,2-d]oxazole derivatives were obtained and characterized by the spectral data and elemental analysis. In addition, the X-ray crystal structures of 2-[4-(N,N-dimethylamino)phenyl]naphtho[ 1,2-d] oxzole (3d) and 1, 1'-bis(naphtho[ 1,2-d]oxazol-2-yl)ferrocene (3n) have been determined.
出处 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2007年第11期1704-1709,共6页 中国化学(英文版)
基金 Project supported by the National Natural Science Foundation of China (No. 20472074) and the Innovation found for 0utstanding Scholars of Henan Province (No. 0621001100).
关键词 2-arylnaphtho[1 2-d]oxazole 1-amino-2-naphthol derivative TRIETHYLAMINE crystal structure 2-arylnaphtho[1,2-d]oxazole, 1-amino-2-naphthol derivative, triethylamine, crystal structure
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