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海洋新放线菌及其次级代谢产物研究进展 被引量：21

Recent progress in the discovery of new marine-derived actinomycetes and their secondary metabolites
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摘要 由于自身特殊的生存环境,海洋放线菌具有复杂独特的代谢途径,产生了诸多结构新颖、生物活性显著的次级代谢产物,这些活性代谢产物为新抗生素的发现提供了丰富的先导化合物,有些已经进入临床前研究。本文简要介绍近十几年从海洋样品中分离到的放线菌新种属及其次级代谢产物研究概况。 Due to the complex metabolic capabilities, special living environment, marine-derived actinomycetes possess distinct and resulting in wide diversity of their secondary metabolites in chemical structure and biological activity. Among them, many valuable leading compounds were obtained for discovery of new antibiotics, and some had been selected for preclinical study. The research advances in discovery of new actinomycetes and their secondary metabolites were briefly reviewed in this paper.
作者 王淑霞 朱天骄 卢圳域 顾谦群 朱伟明
机构地区 教育部海洋药物重点实验室山东省海洋药物重点实验室中国海洋大学医药学院
出处 《中国抗生素杂志》 CAS CSCD 北大核心 2007年第9期513-519,共7页 Chinese Journal of Antibiotics
基金 国家863计划(2007AA09244)。
关键词 海洋放线菌 代谢产物 Salinispora Verrucosispora Marinispora Marine-derived actinomycetes Metabolites Salinispora Verrucosispora Marinispora
分类号 Q71 [生物学—分子生物学]
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参考文献37

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中国抗生素杂志
2007年 第9期

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