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急性非淋巴细胞白血病患者NK细胞亚群及其NCR受体测定 被引量:9

Detection of NK cell subsets and natural cytotoxicity receptor expression of acute non-lymphocytic leukemia by flow cytometry
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摘要 目的:探讨初发的急性非淋巴细胞白血病患者NK细胞亚群分布及自然细胞毒受体(NCR)的水平。方法:应用流式细胞仪技术测定26例初发急性非淋巴细胞白血病患者外周血NK细胞、NK细胞亚群、自然细胞毒受体。结果:初发急性非淋巴细胞白血病患者外周血NK细胞明显低于对照组(P<0.01),CD56bright及CD56d imNK细胞明显低于正常对照组(P<0.01),NKp30、NKp44、NKp46在CD56+CD3-细胞中的表达均低于正常对照组(P<0.05)。结论:急性非淋巴细胞白血病发病可能与NK细胞及亚群减低,自然细胞毒受体表达降低有关。
出处 《中国病理生理杂志》 CAS CSCD 北大核心 2007年第10期2063-2064,共2页 Chinese Journal of Pathophysiology
关键词 白血病 非淋巴细胞 急性 杀伤细胞 天然 受体 自然细胞毒 Leukemia, nonlymphocytic, acute Killer cells, natural Receptors, natural cytotoxicity
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参考文献7

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