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新生儿肠闭锁改良肠单层吻合术的实验研究及临床应用 被引量:14

Experimental research of modified single-layer intestinal anastomosis and its clinical application in neonates with intestinal atresia
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摘要 目的:探索良好的肠吻合术式,以防止肠闭锁之小口径肠管吻合术后吻合口梗阻的发生。方法:改良肠单层吻合术与全层内翻吻合术进行动物实验比较,并临床应用。结果:切片观察示吻合口粘膜连续性恢复好,粘膜缺损少,粘膜下移少而轻,粘膜下层对合满意。与全层内翻吻合比较有统计学差异。术后2周吻合口标本羟脯氨酸含量(代表胶原含量)实验组与对照组分别为43.527μg/mg 干重和41.423μg/mg 干重(P>0.05)。7例肠闭锁患儿手术效果满意。结论:改良肠单层吻合术不仅简便省时,而且有利于吻合口愈合,防止吻合口梗阻发生,尤其适用于小口径肠管。 Objective:To find a way of intestinal anastomosis to reduce the incidence of anas- tomosis obstruction in the treatment of neonatal intestinal atresia.Methods:The modified single- layer intestinal anastomosis was performed on and compared with the two-layer intestinal anasto- mosis in dogs.The some anastomosis was also performed on 7 neonates with intestinal atresia. The anastomosis line of the two methods were observed under microscope.Results:Two weeks after the experiments,the hydroxyproline concentrations(standing for collagen concentration)in the suture lines were 43.527 μg/mg dry weight and 41.423 μg/mg dry weight in the modified sin- gle-layer suture group and two-layer suture group respectively.Seven newborns with intestinal a- tresia were operated by the modified single-layer suture method without stenosis or leakage.Con- clusions:The modified single-layer anastomosis is easy,time-saving and preventing early obstruc- tion following the anastomosis of tiny calibre of neonatal intestine
出处 《中华小儿外科杂志》 CSCD 1997年第2期94-96,共3页 Chinese Journal of Pediatric Surgery
关键词 新生儿 肠闭锁 肠单层吻合术 Neonatel surgery Intestinal atresia Single-layer intestinal anastomosis
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参考文献1

  • 1陈永卫,中华小儿外科杂志,1988年,9卷,359页

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