摘要
目的观察光量子藻酸双酯钠液体载氧疗法对前部缺血性视神经病变和视网膜静脉阻塞高血黏度的改善作用。方法本院眼底病组住院患者159例,根据病史、眼底特征、视野检测和或日产Topcon50VT相机荧光素眼底血管造影确诊,将血流变检测异常者纳入,其中缺血性视神经病变患者73例,视网膜静脉阻塞患者86例,对照组采用藻酸双酯钠常规静脉给药观察,治疗组采用藻酸双酯钠光量子载氧两组治疗,仪器使用长春产CYZ-2型氧透射载体治疗仪,将静脉注射药物藻酸双酯钠加入5%葡萄糖250ml通过氧载体输液器在氧载体透照窗经过石英管进行紫外线照射后输入体内,强度为2.5×1000Uw,透照时间〉60min,每日一次,治疗10d后复查血液流变和血脂,对血流变和血脂指标进行统计学分析。结果依据异常血液变和血脂指标改善情况,藻酸双酯钠药物常规治疗和光量子载氧治疗后除均能降低患者高切黏度、低切黏度、胆固醇或甘油三酯;光量子载氧治疗后在高切黏度、低切黏度和胆固醇指标上疗效明显增加（p〈0.05）。结论藻酸双酯钠光量子载氧疗法对前部缺血性视神经病变和视网膜静脉阻塞患者高血黏度的恢复有明显效果,能显著增加药物的治疗作用无创伤,值得应用。
Objective To investigat Light quantum to carry oxygen unite alginic sodium diester drug treatment on the changes of hemorrheologic behavior and the level of blood lipid for anterior ischemic optic neuropathy （AION） and retina vein occlusion （RVO）. Methods A total of 159 patients with AION and RVO, selected from the center of The Fourth Hospital of XT AN, were divided into three groups by hemorrheologic behavior, randomly divided into treatment and conrtol group by man and female. In order to amelioration the abnormal hemorrheologic blood behavior, the conrtol group with 74 patients were treated with alginic sodium diester 250 mg in 5% glucose solution iv. drip, qd. the treatment groups with 75 patients were given alginic sodium diester and the same tima accepted CYZ-2 type oxygen transmission therapautics made in changchun. After addin 5% glucose 250ml pass carrier infussion apparatu with quartz procee ultraviolet radiation, the drug used to injection of vein. Hematocrit （HCT）, fibrinogen, cholesterol, TG and other items were examined befour and after the therapy. Before and after 10 day treatment, the changes of hemorheology and blood lipid were observed and compared respectively in each pare. The results in different groups is analysized retrospectively. Results The results showed that indices of hemorheology in different groups were markedly reduced （p〈0. 05）. The effect of treatment groups were greater than that of control groups. Some index of hemorheology were significant difference compared with those of control group bdfore and after treatment （p 0.01 ro 0.05）. Conclusion Light quantum to carry oxygen unite alginic sodium diester drug treatment on high bolld viscosity is different for abnormily hemorrheologic behavior recovery. Choosing suitable drug is better for the therapeutic efficacy on treating AION and RVO.
出处
《中国实用眼科杂志》
CSCD
北大核心
2007年第7期705-708,共4页
Chinese Journal of Practical Ophthalmology
关键词
血流变
光量子药物载氧
藻酸双酯钠
药物治疗
Anterior ischemic optic neuropathy
Retinal vein occlusion hemorrheology
Hemorrheologic behavior
A
ginic sodium diester
