摘要
目的通过研究急性冠脉综合征(ACS)患者血清超敏C反应蛋白(hs-CRP)的变化,探讨其与冠状动脉狭窄程度的相关性。方法选取60例ACS患者,对照组50例,采用免疫比浊法测定hs-CRP,所有ACS患者进行冠状动脉造影对冠脉血管进行损害程度评分,研究hs-CRP与冠状动脉狭窄范围及程度的关系。结果ACS组hs-CRP高于对照组(P<0.01)。冠脉多支病变组hs-CRP高于单支病变组(P<0.01),闭塞组hs-CRP高于狭窄组(P<0.01)。结论测定ACS患者hs-CRP对其冠状动脉狭窄范围及程度有一定的预测价值。
Objective To explore the relationship between hypersensitive C-reactive protein(hs-CRP)and the stenosis degree of the coronary artery in patients with acute coronary syndrome(ACS).Methods Sixty patients with ACS confirmed by coronary angiography and 50 controls with a chest pain but no ischemic changes in ECG and no coronary heart disease confirmed by coronary angiography were recruited in this study.The level of hs-CRP was measured by immunoturbidimetric assay.Results The level of hs-CRP in patients with ACS was higher than that in controls;hs-CRP in patients with multiple-vessel diseases was higher than that in patients with single-vessel disease;and hs-CRP in patients with coronary occlusion was higher than that in patients with coronary stenosis.Conclusion The level of hs-CRP could be an index to indicate the stenosis range and degree of the coronary artery.
出处
《山西医科大学学报》
CAS
2007年第8期719-720,共2页
Journal of Shanxi Medical University