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介孔分子筛孔道结构对药物巯甲丙脯酸释放性能的影响 被引量：11

Effect of Mesoporous Silica Pore Structure on the Release Profiles of Captopril Drug
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摘要 A series of mesoporous silica with variable pore structures were prepared.The influence of mesoporous structure on drug release profiles was studied.It is found that mesoporous pore structure has a great effect on the drug release rate.The cubic pore structure MCM-48 has a faster drug release rate than that of MCM-41 system;while SBA-16 with 'cage-like' pore structure system has the lowest drug release rate. A series of mesoporous silica with variable pore structures were prepared. The influence of mesoporous structure on drug release profiles was studied. It is found that mesoporous pore structure has a great effect on the drug release rate. The cubic pore structure MCM-48 has a faster drug release rate than that of MCM-41 system; while SBA-16 with ＂cage-like＂ pore structure system has the lowest drug release rate.
作者 曲凤玉 崔凌飞 黄世英 朱广山
机构地区 哈尔滨师范大学化学系 吉林大学无机合成与制备化学国家重点实验室
出处 《高等学校化学学报》 SCIE EI CAS CSCD 北大核心 2007年第8期1440-1442,共3页 Chemical Journal of Chinese Universities
基金 国家自然科学基金(批准号:29873017 20101004)资助
关键词 介孔分子筛 孔道结构 巯甲丙脯酸 释放性能 Mesoporous silica Pore structure Captopril Release property
分类号 O614 [理学—无机化学]
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参考文献12

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二级参考文献4

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共引文献21

同被引文献147

  • 1曲凤玉,朱广山,黄世英,李守贵,裘式纶.水溶性药物巯甲丙脯酸/Si-MCM-41载药新体系的制备与缓释作用研究[J].高等学校化学学报,2004,25(12):2195-2198. 被引量：16
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引证文献11

二级引证文献44

高等学校化学学报
2007年 第8期

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