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巯基乙酸经皮生殖毒性的研究 被引量:18

A STUDY ON REPRODUCTIVE TOXICITY OF THIOGLYCOLLIC ACID THROUGH PERCUTANEOUS ADMINISTRATION
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摘要 本项研究检测了巯基乙酸(TGA)90天经皮染毒大鼠的发情周期、精子的数目、形态和活动能力,并观察了TGA对卵巢和睾丸超微结构的影响。结果表明,TGA经皮侵入可引起大鼠生殖系统的明显损害。 Thioglycollic acid (TGA) was administered to rats of both sex by dermal application during a period of 90 days. The estrus cycle and the count, morphological change and motility of sperms were examined, and the changes of testis and ovarium in ultrastructure were observed. The results showed that the reproductive system of rats could be obviously damaged when TGA has been absorbed per cutem.
出处 《工业卫生与职业病》 CAS CSCD 1990年第3期141-145,共5页 Industrial Health and Occupational Diseases
关键词 巯基乙酸 皮肤 牛殖毒性 thioglycollic acid endermic reproductive toxicity
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参考文献3

  • 1黄权光,史纪兰,商希梅.尼卡巴嗪对大鼠精子形态的影响[J]卫生研究,1989(01).
  • 2高青.一种改进的小鼠精子畸形检测方法[J]卫生研究,1989(01).
  • 3李百祥,赵新华,武丽杰,周威.冷烫精的致突变效应[J]卫生毒理学杂志,1988(03).

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