摘要
本文研究的目的是以蝌蚪微核及ＣＨＯ培养细胞染色体畸变（ＣＡ）及姐妹染色单体交换（ＳＣＥ）为指示器，研究昆明市各水厂自来水和它们源水的潜在致突变性。结果表明：①各水厂自来水及它们的源水诱发蝌蚪微核率，除Ｙ－水厂自来水外都有显著性差异。②ＣＡ率的结果：各水厂自来水及源水和对照组除了Ｗ－水厂自来水外，都没有显著性差异。③ＳＣＥ率：高浓度组（０．０６２５Ｌ／ｍｌ）的滇池源水及Ｗ－水厂自来水和低浓度组（０．０３１２５Ｌ／ｍｌ）的Ｗ－水厂自来水同对照组相比，有极显著性差异。低浓度组滇池源水和高浓度组的Ｅ－，Ｓ－水厂自来水有显著性差异。
This study is aimed to investigate the potential mutagenicity of tap water and theirsource water from water plants in Kunming with tadpole micronuclei and chromosomalaberrations(CA)and sister chromatid exchages(SCEs)tests of cultured CHO cells. The results revealed: ① There is an obvious difference on frequency of tadpole micronucleus induced between each water plant tap water and its source water with the exception of y-water plant tap water. ② The results of CA frequency showed no substantial difference betweeneach water plant tap water and its source water and control group except of low concentration (0.03125 L / ml) group of W-water plant tap water. ③ There is an extremly significantdifference between the high concentration groups 0.0625 L / ml (Dianchi Lake source waterand W-water plant tap water),and low concentration group (W-water plant tap waterthrough comparison with control group) with SCE frequency. There is a significant differencein low concentration group of Dianchi Lake source water and high concentration group ofE-, S-water plant tap water.
基金
云南省科学技术委员会应用基础研究基金
