摘要
冠心病伴左室舒张功能不全患者 １３４例，随机分为两组，治疗组 ６８ 例，服用茶色素 １２５ｍｇ，每日 ３次。对照组 ６６例，服用卡托普利 １２．５ｍｇ，每日 ３次。 疗程约为 ３０天。结果：治疗组服药后ＰＥ、ＥＳ明显增加（Ｐ＜０．０１），ＰＡ、ＡＳ明显下降 （Ｐ＜０．０１－０．０５），ＰＡ／ＰＥ、ＡＳ／ＥＳ比值下降（Ｐ＜０．０１），ＤＣ增块（Ｐ＜０．０５）。对照组 除ＰＥ、ＥＳ、ＡＳ变化较明显外（Ｐ＜０．０５），其余变化不显著（Ｐ＞０．０５）。治疗组尚有明 显降低血脂、血粘度、改善微循环及心电图的功效，并初步探讨了茶色素改善冠心 病左室舒张功能的机理。
134 cases of coronary heart disease accompanied with diastolic iusufficieney of left ventrical were randomly divided into two groups, 68 cases being in the therapeutic group taking 125mg of teapigment; 3times a day, 66 cases in the control group taking 12. 5mg of captopril 3 times a day,with a course of treatment for 30 days. The result showed that in the therapentic group,after medieation the value of PE and ES both increased re- markably (P<0. 01 )while the value of PA and AS both macreased remarkably (P<0. 01 - 0. 05) and while the ratio of PA/PE and AS/ES descended(P<0. 01 ) the value of DC quckened (P<0.05 ) and in the control group,after medication,except for a comparatively remarkable change in the value of PE,ES and AS (P<0.05),there was no obvious change in the others (P>0.05) and also in the Herapeutic group there was obvious efficiency of reduc- ing blood -lipid and blood viscosity and improving microtirculation and ECG. This paper gives a preliminary approach to the mechanism of teapigment in improving coronary heart disease with diastolic in sufficiency of left ventricle.
出处
《中国血液流变学杂志》
CAS
1997年第1期30-34,16,共6页
Chinese Journal of Hemorheology
关键词
茶色素
左室舒张功能
卡托普利
冠心病
teapigment, Coronary heart disease
Captopril
Doppler ultrasound echecardiograph.
