摘要
[目的]了解大学新生乙型肝炎病毒感染状况与相关因素,探讨乙肝预防对策。[方法]酶联免疫法测定2 797名大学新生乙肝表面抗原,阳性者测定乙肝5项血清标志物;贝克曼CX9自动生化分析仪测定肝功;问卷调查乙肝相关情况。[结果]2 797名大学新生HBsAg阳性率8.51%,性别、城乡、省内外学生间差异有统计学意义(χ2=15.617,χ2=18.94,χ2=38.64,P﹤0.05),汉族与少数民族学生差异无统计学意义;HBsAg阳性者BeAg阳性率41.18%;检出HBV标志物阳性模式9种,以HBsAg、HBeAb、HBcAb阳性(42.86%)和HBsAg、HBeAg、HBcAb阳性(22.27.%)居多;HBsAg阳性组肝功异常明显高于HBsAg阴性组(χ2=57.36,P﹤0.05);HBeAg阳性组肝功异常明显高于HBeAg阴性组(χ2=61.45,P﹤0.05);乙肝疫苗接种、家庭肝病史、卫生习惯等影响HBV感染;27.14%的学生对HBV感染存在错误认识;HBV感染对学生心理产生不良影响。[结论]HBV感染在部分大学新生中具有较高感染率,HBV感染与学生知识、态度、行为有关;把HBV列入新生体检必查项目;加大预防HBV感染知识宣教深度与力度;加强感染HBV学生健康教育与心理咨询。
[ Objective] To investigate the situation of HBV infection and the correlative factors in university freshmen. and to discuss prevention strategies. [Methods] A total of 2 797 university freshmen were tested HBsAg Ly ELISA, and the five serum markers of hepatitis B were examined in HBsAg positive students. The live function was analyzed by CX9 atttotnatic biochemical analyzer. Questionnaire survey was conducted to collect hepatitis B related situation. [ Results] The positive rate of HBsAg was 8.51% in 2 797 university freshmen. No significant difference was detected between Han people and minority , but significant differences were found between male and female, the students from city and cottntry and the ones in and otlt of Sichuan province （X^2 = 15.617, X^2= 18.94, X^2= 38.64, P〈 0.05）. The positive rate of HBeAg was 41.18% in HBsAg positive students. There were 9 kinds of HBV serum markers positive mo,dels, in which the two major models were tiP, sAg （＋）, HBeAb （＋）, HBcAb （＋）（42.86%） and HBsAg （＋）, HBeAg （＋）, HBcAb （＋）（22.27%）. Liver tractions of HBsAg positive students were significant higher than those of HBsAg negative students （X^2 = 57.36, P 〈 0.05）, and the liver functions of HBeAg positive students were significanfly higher than those of HBeAg negative students （X^2 = 61.45, P 〈 0.05）. Inoculation history of hepatitis B vaccine, HBV infection family history, health habit, economical condition couht ＇affect HBV infection rate; 27.14% students did not have correct HBV infection information. HBV infection had some negative effect on the students mental health. [Conclusion] HBV infection rate is still higher in some university freshmen, and HBV infection has correlation with the knowledge, attitude and practice of students. HBV infection must be included in physical exarnination for freshets. The propaganda of knowledge about HBV infection should be promoted furtherly in depth and strength, and health education and psychological counselling of the students with HBV infection should be enforced.
出处
《现代预防医学》
CAS
北大核心
2007年第15期2940-2943,共4页
Modern Preventive Medicine
基金
四川内江市科技项目(2006.0.1)
