摘要
目的:探讨肾粘液管状梭形细胞癌的临床特点。方法:报告1例左肾粘液管状梭形细胞癌患者的临床资料并复习有关文献。本例以持续高热、食欲减退等症状就诊。行肾癌根治术,肿瘤约6.0cm×6.5cm,临床分期为T4N2M0;病理表现为排列成簇的狭长小管状上皮细胞,中间充满粘液间质和梭形细胞,核分裂像少见;免疫组化E-cadherin(+)、CK17(+)、CD10(-)、CD15(-)。结果:术后第1天体温恢复正常,随访16个月未见肿瘤复发和转移。结论:肾粘液管状梭形细胞癌是一类低度恶性的肾上皮性肿瘤,可能来源于远端肾小管,早期手术是其首选的治疗方法。
Objective：To investigate the clinical and pathologic feature and cell origin of renal mucinous tubular and spindle cell carcinoma（MTSCC）. Methods：The clinical date of 1 case renal MTSCC was retrospectively ana lyzed and discussed with literature reviewed. The patient came to hospital with complaint of fever and poor appetite. The size of the tumor was 6.0 - 6. 5 cm. Clinical stage： T4N2M0. Histologic feature： tumors consisted of tightly packed, small, elongated tubules separated by pale mucinous stroma. The tumor cells were cuboidal to spindled with eosinophilic cytoplasm and low nuclear grade. The Immunohistochemical staining of the tumor was positive for E-cadherin and CK17, negative for CD10 and CD15. Results：The case was followed 16 months afte rad ical nephrectomy, no recurrence and metastasis were found. Conclusions： MTSCC of the kidney is a distinctive lowgrade renal carcinoma probably originating from distal tubule. Early surgery is the preferred treatment.
出处
《临床泌尿外科杂志》
2007年第7期535-537,共3页
Journal of Clinical Urology
关键词
肾肿瘤
病理学
Tumor of kidney
Pathology
