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氯普鲁卡因及芬太尼缩短硬膜外罗哌卡因起效时间的临床观察

A CLINICAL OBSERVATION OF CHLOROPROCAINE OR FENTANYL SHORTEN ONSET PERIOD OF EPIDURAL ROPIVACAINE
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摘要 目的探讨妇科手术患者复合氯普鲁卡因及芬太尼对罗哌卡因硬膜外麻醉起效时间的影响。方法择期妇科手术患者60例,随机分为Rc,Rf,R三组,硬膜外分别给予0.75%罗哌卡因18ml+氯普鲁卡因200mg+生理盐水2ml;0.75%罗哌卡因18ml+芬太尼0.1mg/2ml;0.75%罗哌卡因18ml+生理盐水2ml。记录感觉阻滞最高平面、感觉阻滞起效时间、血流动力学改变及不良反应。结果感觉阻滞平面达T10的时间Rc、Rf组均明显短于R组,Rc组短于Rf组;最高阻滞平面Rc、Rf组均明显短于R组。结论氯普鲁卡因200mg与芬太尼0.1mg均可缩短罗哌卡因硬膜外阻滞起效时间,且复合氯普鲁卡因200mg较芬太尼0.1mg起效时间更短。 Objective To explore how chloroprocaine or fentanyl affects the onset time of epidural ropivacaine on operation of gynecologic patients. Methods 60 patients scheduled for selective gynecologic surgery were randomly assigned to 3 groups: group Rc, which received 0.75% ropivacaine 18ml plus chloroprocaine 200mg plus Normal saline solution 2ml; group Rf, which received 0.75% ropivacaine 18ml with fentanyl 0. lmg/2ml; group R, which received 0.75% ropivacaine 18ml with Normal saline solution 2ml. The peak block plane, onset time of sensation block, haemodynamic change and reverse effects were observed and recorded. Results The time to receive sensation block at T10 in group Rc and Rf was sig- nificantly shorter than that in group R, and that in group Rc was shorter than that in group Rf. The time to receive sensation block at peak block plane in group Rc and Rf was significantly shorter than that in group R. Conclusion Either chloro- procaine 200mg or fentanyl 0. lmg can shorten the onset time of epidural ropivacaine, furthermore, the onset time of chloro- procaine 200mg addition is shorter than that of fentany 0. lmg addition.
出处 《中国煤炭工业医学杂志》 2007年第8期886-887,共2页 Chinese Journal of Coal Industry Medicine
基金 天津医科大学总医院科研课题
关键词 氯普鲁卡因 罗哌卡因 芬太尼 硬膜外阻滞麻醉 起效时间 chloroprocaine ropivacaine fentanyl epidural block onset time
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参考文献6

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二级参考文献14

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