摘要
自从德国生理学家JohannesMfieller于1838年首次提出“胆脂瘤”概念以来.各家学者对其发病机制的研究作了大量的工作,但其局部的膨胀压迫性生长和骨破坏性作用机制仍不明了。后天性胆脂瘤的临床特征是以复层鳞状上皮向中耳腔内生长,形成囊袋,角化上皮组织不断堆积,逐渐扩展累及邻近结构导致听力损失、前庭功能障碍、面神经麻痹和颅内外一系列并发症。本文复习既往的文献对中耳胆脂瘤的发病机制及分子生物学基础的论述。
出处
《中华耳科学杂志》
CSCD
2007年第2期168-170,共3页
Chinese Journal of Otology
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