摘要
为了提高对肺癌伴胸膜转移和癌性胸水病人的治疗效果,采用胸膜全肺切除方法治疗肺癌伴胸膜转移和癌性胸水病人7例。无手术死亡,1例术后12个月死于脑转移,6例健在,已生存8~28个月,明显高于内科治疗效果。认为该手术可以明显缓解症状,减轻瘤负荷,清除胸水中的免疫抑制因子,为后续的综合治疗创造条件。作者提出了术中最大限度切除肿瘤的有关方法。指出术中最大限度的清除肿瘤组织,对可能残存肿瘤组织部位做有效的处理及术后全身和局部的综合治疗是提高长期生存率的关键。
In order to improve the therapeutic effect of pulmonary carcinoma complicated with diffuse pleural metastasis and malignant pleural effusion,7 cases of total pleuro pneumonectomy were performed with no operative death,of which,1 case died from the cerebral metastasis in the 12th month after the operation,other 6 cases were survived whose survival period was 8 28 months,which is obviously longer than that of conservative treatment,The relevant methods about the tumor excision of maximal limitation during operation were given in the article.It was believed that the operation could relieve the symptoms obviously,lighten the tumor load and clean immunodepressive factors in pleural effusion,which could creat favourable conditions for the follow up comprehensive therapy.It is pointed out that the tumou excision of maximal limitation during operation,the effective management of the residual tumor tissue and the post operative whole body and local comprehensive therapy are the cruxes to increase the long term survival rate.
关键词
胸膜
胸水
肺切除
肺肿瘤
Pulmonary carcinoma Pleura Pleural effusion surgical treatment