摘要
目的:探讨防风颗粒与利巴韦林颗粒对小儿轮状病毒肠炎的临床与经济学效果。方法:小儿轮状病毒肠炎50例,随机均分为A、B组。A组口服防风颗粒40mg.kg-1.次-1,tid;B组给予利巴韦林颗粒10mg.kg-1.d-1,分3次口服,疗程均为3d。结果:A组与B组临床总有效率分别为92.0%、80.0%(P<0.05),成本分别为194.70、192.95元,成本-效果比分别为211.63、241.19。结论:防风颗粒治疗小儿轮状病毒肠炎较利巴韦林颗粒疗效好,不良反应少,更经济。
OBJECTIVE: To compare the efficacy between fangfeng granula and ribavirin granula in the management of rotavirus enteritis in children.METHODS: A total of 50 children with urinary system infection were randomly assigned to receive fangfeng granula 40mg · kg^-1 each time tid for 3 days(Group A) or ribavirin granula 10mg · kg^-1 · d^ -1 in 3 divided doses for 3 days (Group B). RESULTS: The total effective rates for Group A and B were 92.0 % and 80.0 %, respectively (P 〈 0.05). The costs were 194.70,192.95 yuan, respectively. The costeffectiveness ratios were 211.63 and 241.19, respectively. CONCLUSION :As compared with ribavirin granula, Fangfeng granula has better efficacy and more economical but less ADR in treating rotavirus enteritis in children.
出处
《中国药房》
CAS
CSCD
北大核心
2007年第20期1524-1525,共2页
China Pharmacy