摘要
代谢综合征是以中心性肥胖、胰岛素抵抗、高血压、高三酰甘油血症、低高密度脂蛋白胆固醇、糖耐量下降或2型糖尿病为主要特征的症候群,其病因学以肥胖为核心,同时遗传和环境因素、精神因素也是很重要的两个原因。发病机理主要以胰岛素抵抗为核心,其他脂肪细胞因子如抵抗素、脂联素、瘦素、肿瘤坏死因子-α等在发病中均起了很重要的作用。
Metabolic syndrome is characterised by abdominal fat, high triglycerides, hypertension, low HDL-c, impaired glucose intolerance or type 2 diabetes mellitus. The central etiology is fat, and other important factors are inheritance, and environmental and psychological factors. The main pathogenesis is insulin resistance. The other adipocytokines such as resistine, adiponectin, leptin and TNF-α all play important roles in the pathogenesis of metabolic syndrome.
出处
《心血管病学进展》
CAS
2007年第4期587-590,共4页
Advances in Cardiovascular Diseases
