摘要
目的为了解艾滋病(HIV)职业暴露现状,探讨职业暴露后应急预防处理的影响因素。方法对浙江省2002～2005年报告的由于职业因素引起的HIV暴露案例进行调查并统计分析。结果44起56人包括医务人员,公安司法职业暴露,暴露类型包括针头刺伤,抓咬伤和血液接触皮肤或粘膜,50人实施暴露后预防(PEP),有43人采用基本用药程序进行干预治疗,占76.8%(43/56);有7人采用强化用药程序;有6人自愿不实施PEP。目前所有病例随访未发现HIV抗体阳转者,有一例发生丙肝病毒(HCV)抗体阳转。结论HIV职业暴露后感染的危险度较低,但是要注意加强对其他各类血液传播疾病的阻断防护。
Objective To investigate the occupational exposure status of HIV and discuss the influence factors of post exposure prophylaxis （PEP）. Methods Occupational exposure eases of HIV diagnosed during 2002- 2005 in Zhejiang Province were investigated and statistically analyzed. Results There were 56 cases, including medical professionals and polices, occupationally exposed to HIV with the exposure type involving needle stick injuries, scratching and biting injuries, and blood contacting of skin or mucosa. Among these eases, .50 accepted post-exposure prophylaxis, 76.8% （43/56） were applied intervention treatment by traditioal medications, 7 cases were applied strengthening medications, and 6 cases voluntarily agreed to treatment without PEP. Although one ease who carries HCV antibody converted into HCV positive, none of them were observed serum conversion of HIV during the follow-up. Conclusions The risk of HIV infection after occupational exposure is very low. But other blood disseminated diseases should be paid attention to, and preventing and interrupting measures need to be put forward.
出处
《浙江预防医学》
2007年第7期1-2,共2页
Zhejiang Journal of Preventive Medicine
关键词
艾滋病
职业暴露
暴露后预防
HIV
Occupational exposure
Post-exposure prophylaxis
